Analysis of the susceptibility to COVID-19 in pregnancy and recommendations on potential drug screening

X Zhao, Y Jiang, Y Zhao, H Xi, C Liu, F Qu… - European Journal of …, 2020 - Springer
To analyze the susceptibility of SARS-CoV-2 in pregnancy and the drugs that can be used to
treat pregnancy with COVID-19, so as to provide evidence for drug selection in clinic. By …

[HTML][HTML] Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential

H Kheraldine, O Rachid, AM Habib… - Advanced drug delivery …, 2021 - Elsevier
Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …

Dendrimer as nanocarrier for drug delivery

P Kesharwani, K Jain, NK Jain - Progress in Polymer Science, 2014 - Elsevier
Dendrimers are novel three dimensional, hyperbranched globular nanopolymeric
architectures. Attractive features like nanoscopic size, narrow polydispersity index, excellent …

Nanomedicine (s) under the microscope

R Duncan, R Gaspar - Molecular pharmaceutics, 2011 - ACS Publications
Depending on the context, nanotechnologies developed as nanomedicines (nanosized
therapeutics and imaging agents) are presented as either a remarkable technological …

Polymeric conjugates for drug delivery

N Larson, H Ghandehari - Chemistry of Materials, 2012 - ACS Publications
The field of polymer therapeutics has evolved over the past decade and has resulted in the
development of polymer–drug conjugates with a wide variety of architectures and chemical …

[HTML][HTML] Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National …

JV Ilekis, E Tsilou, S Fisher, VM Abrahams… - American journal of …, 2016 - Elsevier
Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …

Endocytosis and intracellular trafficking as gateways for nanomedicine delivery: opportunities and challenges

R Duncan, SCW Richardson - Molecular pharmaceutics, 2012 - ACS Publications
More than 40 nanomedicines are already in routine clinical use with a growing number
following in preclinical and clinical development. The therapeutic objectives are often …

The placental barrier: the gate and the fate in drug distribution

N Tetro, S Moushaev, M Rubinchik-Stern… - Pharmaceutical …, 2018 - Springer
Optimal development of the embryo and the fetus depends on placental passage of gases,
nutrients, hormones, and waste products. These molecules are transferred across the …

Nanoparticles in pregnancy: the next frontier in reproductive therapeutics

N Pritchard, T Kaitu'u-Lino, L Harris… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Nanotechnology involves the engineering of structures on a molecular
level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic …

Polymer therapeutics as nanomedicines: new perspectives

R Duncan - Current opinion in biotechnology, 2011 - Elsevier
A growing number of polymer therapeutics have entered routine clinical use as nano-sized
medicines. Early products were developed as anticancer agents, but treatments for a range …