Investigating the aggregation of amyloid beta with surface plasmon resonance: Do different approaches yield different results?

KA Young, RL Mancera - Analytical Biochemistry, 2022 - Elsevier
Aggregation of amyloid beta into amyloid plaques in the brain is a hallmark characteristic of
Alzheimer's disease. Therapeutics aimed at preventing or retarding amyloid formation often …

The properties of amyloid-β fibrils are determined by their path of formation

K Brännström, T Islam, AL Gharibyan, I Iakovleva… - Journal of molecular …, 2018 - Elsevier
Fibril formation of the amyloid-β peptide (Aβ) follows a nucleation-dependent polymerization
process and is associated with Alzheimer's disease. Several different lengths of Aβ are …

[HTML][HTML] Analysis of Amyloid Fibrillation of Two Family 1 Glycoside Hydrolases

MA Rodríguez-López, JM Coll-Marqués… - International Journal of …, 2024 - mdpi.com
The formation and analysis of amyloid fibers by two β-glucosidases, BglA and BglB,
belonging to the GH1 enzyme family, are reported. Both proteins have the (β/α) 8 TIM-barrel …

Concentration‐Dependent Interactions of Amphiphilic PiB Derivative Metal Complexes with Amyloid Peptides Aβ and Amylin

S Majdoub, Z Garda, AC Oliveira… - … A European Journal, 2021 - Wiley Online Library
Metal chelates targeted to amyloid peptides are widely explored as diagnostic tools or
therapeutic agents. The attachment of a metal complex to amyloid recognition units typically …

Assessment of Amyloid Morphology Using Electron Microscopy

LR Adil, V Ramakrishnan - Biophysical Characterization of Functional …, 2023 - Springer
A β amyloid fibrils have been demonstrated to be vital for triggering Alzheimer's disease, as
reported by numerous research works. Therefore, A β amyloid fibrils formation is considered …

[PDF][PDF] Silybins as multi-target proteostasis rescuers in Alzheimer's Disease and Type II Diabetes Mellitus

SG VIÑUALES - iris.unict.it
A defective protein folding and its abnormal aggregation and accumulation is the central
pathogenic event in Protein Conformational diseases (PCDs), such as Alzheimers Disease …

Silybins as multi-target proteostasis rescuers in Alzheimer's Disease and Type II Diabetes Mellitus

S GARCIA VINUALES - 2020 - tesidottorato.depositolegale.it
A defective protein folding and its abnormal aggregation and accumulation is the central
pathogenic event in Protein Conformational diseases (PCDs), such as Alzheimers Disease …