The Role of MicroRNA in the Pathogenesis of Duchenne Muscular Dystrophy

K Kiełbowski, E Bakinowska, G Procyk… - International Journal of …, 2024 - mdpi.com
Duchenne muscular dystrophy (DMD) is an X-linked progressive disorder associated with
muscle wasting and degeneration. The disease is caused by mutations in the gene that …

[HTML][HTML] Caveolin and NOS in the Development of Muscular Dystrophy

M Nakashima, N Suga, S Yoshikawa… - International Journal of …, 2024 - mdpi.com
Caveolin is a structural protein within caveolae that may be involved in transmembrane
molecular transport and/or various intercellular interactions within cells. Specific mutations of …

NLRP3 Contributes to Sarcopenia Associated to Dependency Recapitulating Inflammatory-Associated Muscle Degeneration

E Antuña, Y Potes, FJ Baena-Huerta… - International Journal of …, 2024 - mdpi.com
Sarcopenia, a complex and debilitating condition characterized by progressive deterioration
of skeletal muscle, is the primary cause of age-associated disability and significantly impacts …

Astaxanthin Ameliorates Worsened Muscle Dysfunction of MDX Mice Fed with a High-Fat Diet through Reducing Lipotoxicity and Regulating Gut Microbiota

Y Chen, C Ling, M Chen, L Yu, J Yang, Q Fang - Nutrients, 2023 - mdpi.com
Duchenne muscular dystrophy (DMD), a severe X-linked inherited neuromuscular disease,
has a high prevalence of obesity. Obesity exacerbates muscle damage and results in …

[HTML][HTML] Cell transplantation-mediated dystrophin supplementation efficacy in Duchenne muscular dystrophy mouse motor function improvement demonstrated by …

CK Bourgeois Yoshioka… - … Cell Research & …, 2024 - stemcellres.biomedcentral.com
Duchenne muscular dystrophy (DMD) is an incurable neuromuscular disease leading to
progressive skeletal muscle weakness and fatigue. Cell transplantation in murine models …

Aronia-derived anthocyanins and metabolites ameliorate TNFα-induced disruption of myogenic differentiation in satellite cells

X Liu, N Shangguan, F Zhang, R Duan - Biochemical and Biophysical …, 2024 - Elsevier
This study investigates the effects of Aronia berries, their primary anthocyanins and other
second metabolites—mimicking dietary anthocyanin consumption—on enhancing muscular …

Enhanced skeletal muscle fatigue tolerance through cell transplantation-mediated dystrophin supplementation in a mouse model of Duchenne Muscular Dystrophy

CKB Yoshioka, N Takenaka-Ninagawa, M Goto, M Miki… - 2023 - researchsquare.com
Background Duchenne muscular dystrophy (DMD) is an incurable neuromuscular disease
leading to progressive skeletal muscle weakness and fatigue. Cell transplantation in murine …

Satellite stem cell dysfunction in Duchenne muscular dystrophy

JA Granet, R Robertson, RL Filippelli, A Cusmano, S Li… - bioRxiv, 2024 - biorxiv.org
Satellite cells are muscle-resident stem cells that maintain and repair muscle. Increasing
evidence supports the contributing role of satellite cells in Duchenne muscular dystrophy …

Profound cellular defects attribute to muscular pathogenesis in the rhesus monkey model of Duchenne muscular dystrophy

S Ren, X Fu, W Guo, R Bai, S Li, T Zhang, J Liu… - Cell, 2024 - cell.com
Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disease caused by
mutations in the DMD gene. Muscle fibers rely on the coordination of multiple cell types for …