Conspectus Deciphering the fluorine code is how we describe not only the focus of this
Account, but also the systematic approach to studying the impact of fluorine's incorporation …

Perfluorocarbons, saturated carbon chains in which all the hydrogen atoms are replaced
with fluorine, form a separate phase from both organic and aqueous solutions. Though …

Tailor-made amino acids are indispensable structural components of modern medicinal
chemistry and drug design. Consequently, stereo-controlled preparation of amino acids is …

A central question in the evolution of the modern translation machinery is the origin and
chemical ethology of the amino acids prescribed by the genetic code. The RNA World …

A Cu-catalysed method that selectively incorporates a trifluoromethyl group and an alkene
moiety onto the α carbon of glycine derivatives has been developed using commercialized …

Catechols are a biologically relevant group of aromatic diols that have attracted much
attention as mediators of adhesion of “bio‐glue” proteins in mussels of the genus Mytilus …

In this comprehensive review, I focus on the twenty E. coli aminoacyl‐tRNA synthetases and
their ability to charge non‐canonical amino acids (ncAAs) onto tRNAs. The promiscuity of …

Within the broad field of synthetic biology, genetic code expansion (GCE) techniques enable
creation of proteins with an expanded set of amino acids. This may be invaluable for …

Fluorination can dramatically improve the thermal and proteolytic stability of proteins and
their enzymatic activity. Key to the impact of fluorination on protein properties is the …

Practical Method for Preparation of (S)-2-Amino-5,5,5-trifluoropentanoic Acid via Dynamic
Kinetic Resolution | ACS Omega ACS ACS Publications C&EN CAS Find my institution Log In …