Is CD34 truly a negative marker for mesenchymal stromal cells?

CS Lin, H Ning, G Lin, TF Lue - Cytotherapy, 2012 - Elsevier
The prevailing school of thought is that mesenchymal stromal cells (MSC) do not express
CD34, and this sets MSC apart from hematopoietic stem cells (HSC), which do express …

The role of podocalyxin in health and disease

JS Nielsen, KM McNagny - Journal of the American Society of …, 2009 - journals.lww.com
Podocalyxin, a sialomucin most closely related to CD34 and endoglycan, is expressed by
kidney podocytes, hematopoietic progenitors, vascular endothelia, and a subset of neurons; …

[HTML][HTML] Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair

A Wilson, E Laurenti, G Oser, RC van der Wath… - Cell, 2008 - cell.com
Bone marrow hematopoietic stem cells (HSCs) are crucial to maintain lifelong production of
all blood cells. Although HSCs divide infrequently, it is thought that the entire HSC pool turns …

Dormant and self‐renewing hematopoietic stem cells and their niches

A Wilson, GM Oser, M Jaworski… - Annals of the New …, 2007 - Wiley Online Library
In the mouse, over the last 20 years, a set of cell‐surface markers and activities have been
identified, enabling the isolation of bone marrow (BM) populations highly enriched in …

[HTML][HTML] CD34-positive stem cells in the treatment of heart and vascular disease in human beings

AR Mackie, DW Losordo - Texas Heart Institute Journal, 2011 - ncbi.nlm.nih.gov
Bone marrow-derived CD34+ cells are a well-characterized population of stem cells that
have traditionally been used clinically to reconstitute the hematopoietic system after …

Not just a marker: CD34 on human hematopoietic stem/progenitor cells dominates vascular selectin binding along with CD44

DB AbuSamra, FA Aleisa, AS Al-Amoodi… - Blood …, 2017 - ashpublications.org
CD34 is routinely used to identify and isolate human hematopoietic stem/progenitor cells
(HSPCs) for use clinically in bone marrow transplantation, but its function on these cells …

The CD34-like protein PODXL and α6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice

RH Lee, MJ Seo, AA Pulin, CA Gregory… - Blood, The Journal …, 2009 - ashpublications.org
We screened for surface proteins expressed only by the early progenitor cells present in low-
passage, low-density cultures of the adult stem/progenitor cells from bone marrow referred …

What makes cancer stem cell markers different?

U Karsten, S Goletz - Springerplus, 2013 - Springer
Since the cancer stem cell concept has been widely accepted, several strategies have been
proposed to attack cancer stem cells (CSC). Accordingly, stem cell markers are now …

[HTML][HTML] The thyroid hormone triiodothyronine controls macrophage maturation and functions: protective role during inflammation

C Perrotta, M Buldorini, E Assi, D Cazzato… - The American Journal of …, 2014 - Elsevier
The endocrine system participates in regulating macrophage maturation, although little is
known about the modulating role of the thyroid hormones. In vitro results demonstrate a …

Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi

JE Galán - Proceedings of the National Academy of …, 2016 - National Acad Sciences
Salmonella Typhi is the cause of typhoid fever, a disease that has challenged humans
throughout history and continues to be a major public health concern. Unlike infections with …