Manganese (Mn) is an essential micronutrient required for the normal development of many
organs, including the brain. Although its roles as a cofactor in several enzymes and in …

Manganese (Mn) is an essential heavy metal. However, Mn's nutritional aspects are
paralleled by its role as a neurotoxicant upon excessive exposure. In this review, we …

Manganese (Mn) is an essential trace element necessary for physiological processes that
support development, growth and neuronal function. Secondary to elevated exposure or …

Microglia are resident cells of the brain involved in regulatory processes critical for
development, maintenance of the neural environment, injury and repair. They belong to the …

Background Excess accumulation of manganese (Mn) in the brain results in a neurological
syndrome with cognitive, psychiatric, and movement abnormalities. The highest …

Manganese (Mn) is an essential trace metal that is pivotal for normal cell function and
metabolism. Its homeostasis is tightly regulated; however, the mechanisms of Mn …

The purpose of this review is to highlight recent advances in the neuropathology associated
with Mn exposures. We commence with a discussion on occupational manganism and …

Human exposure to neurotoxic metals is a global public health problem. Metals which cause
neurological toxicity, such as lead (Pb) and manganese (Mn), are of particular concern due …

Manganese (Mn) is an essential metal and has important physiological functions for human
health. However, exposure to excess levels of Mn in occupational settings or from …

Manganese (Mn) is an essential trace element that is naturally found in the environment and
is necessary as a cofactor for many enzymes and is important in several physiological …