The gate theory of pain, published by Ronald Melzack and Patrick Wall in Science in 1965,
was formulated to provide a mechanism for coding the nociceptive component of cutaneous …

The nature of pain has been the subject of bitter controversy since the turn of the'century (1).
There are currently two opposing theories of pain:(i) specificity theory, which holds that pain …

Recent habituation literature is reviewed with emphasis on neuro-physiological studies. The
hindlimb flexion reflex of the acute spinal cat is used as a model system for analysis of the …

The study of pain in awake animals raises ethical, philosophical, and technical problems.
We review the ethical standards for studying pain in animals and emphasize that there are …

1. In anaesthetized and decerebrate cats isometric exercise of the hind limb muscles was
elicited by stimulating the spinal ventral roots L7‐S1. This caused a rise in arterial blood …

Trigger points associated with myofascial and visceral pains often lie within the areas of
referred pain but many are located at a distance from them. Furthermore, brief, intense …

IN the dorsal part of the dorsal horn there is a lamina of cells which respond to cutaneous
stimulation and send their axons into the dorsolateral tract. In previous investigations1 it was …

Sixty per cent of the cells in the spinocervical tract responding monosynaptically to
stimulation of peripheral myelinated fibers were found to respond also to stimulation of …

Activity in different fibers of a nerve in an animal can be selectively blocked by applying
direct electric current between an anode and a cathode attached to the nerve. The anode …

3,822,708 A: 7/1974 Zilber within the patient's body by applying high frequency Stimu
4,360,026 A 11/1982 Venin et al.................... 607/5 lation and/or direct current pulses at or …