The importance of catalytic promiscuity for enzyme design and evolution
The ability of one enzyme to catalyse multiple, mechanistically distinct transformations likely
played a crucial role in organisms' abilities to adapt to changing external stimuli in the past …
played a crucial role in organisms' abilities to adapt to changing external stimuli in the past …
Expanding the enzyme universe: accessing non‐natural reactions by mechanism‐guided directed evolution
High selectivity and exquisite control over the outcome of reactions entice chemists to use
biocatalysts in organic synthesis. However, many useful reactions are not accessible …
biocatalysts in organic synthesis. However, many useful reactions are not accessible …
To evaluate the toxicity of atrazine on the freshwater microalgae Chlorella sp. using sensitive indices indicated by photosynthetic parameters
C Sun, Y Xu, N Hu, J Ma, S Sun, W Cao, G Klobučar… - Chemosphere, 2020 - Elsevier
Atrazine is a widely-applied herbicide used primarily to control weeds, which can persist in
the ecosystem and exert potential toxicity to phytoplankton in the aquatic environment. In this …
the ecosystem and exert potential toxicity to phytoplankton in the aquatic environment. In this …
Evolution of new enzymes by gene duplication and divergence
SD Copley - The FEBS journal, 2020 - Wiley Online Library
Thousands of new metabolic and regulatory enzymes have evolved by gene duplication and
divergence since the dawn of life. New enzyme activities often originate from promiscuous …
divergence since the dawn of life. New enzyme activities often originate from promiscuous …
Design and optimization of a cell-free atrazine biosensor
Recent advances in cell-free synthetic biology have spurred the development of in vitro
molecular diagnostics that serve as effective alternatives to whole-cell biosensors. However …
molecular diagnostics that serve as effective alternatives to whole-cell biosensors. However …
Atrazine uptake, translocation, bioaccumulation and biodegradation in cattail (Typha latifolia) as a function of exposure time
The extensive use and environmental persistence of atrazine has resulted in its ubiquitous
occurrence in water resources. Some reports have described atrazine bioaccumulation and …
occurrence in water resources. Some reports have described atrazine bioaccumulation and …
Recent trends using natural polymeric nanofibers as supports for enzyme immobilization and catalysis
All the disciplines of science, especially biotechnology, have given continuous attention to
the area of enzyme immobilization. However, the structural support made by material …
the area of enzyme immobilization. However, the structural support made by material …
Evolution of atrazine-degrading capabilities in the environment
Since their first introduction in the mid 1950s, man-made s-triazine herbicides such as
atrazine have extensively been used in agriculture to control broadleaf weed growth in …
atrazine have extensively been used in agriculture to control broadleaf weed growth in …
Persistence of atrazine and trifluralin in a clay loam soil undergoing different temperature and moisture conditions
Dissipation kinetics of atrazine and trifluralin in a clay loam soil was investigated in a
laboratory incubation experiment under different temperature and moisture conditions. The …
laboratory incubation experiment under different temperature and moisture conditions. The …
Evaluation of pesticide residues in fruits and vegetables from the Aegean region of Turkey and assessment of risk to consumers
Pesticides may cause a potential risk to human health when applied in excess to control
pests, diseases, and weeds in crop fields. In the current study, conducted in the Aegean …
pests, diseases, and weeds in crop fields. In the current study, conducted in the Aegean …