The importance of catalytic promiscuity for enzyme design and evolution

RB Leveson-Gower, C Mayer, G Roelfes - Nature Reviews Chemistry, 2019 - nature.com
The ability of one enzyme to catalyse multiple, mechanistically distinct transformations likely
played a crucial role in organisms' abilities to adapt to changing external stimuli in the past …

Expanding the enzyme universe: accessing non‐natural reactions by mechanism‐guided directed evolution

H Renata, ZJ Wang, FH Arnold - … Chemie International Edition, 2015 - Wiley Online Library
High selectivity and exquisite control over the outcome of reactions entice chemists to use
biocatalysts in organic synthesis. However, many useful reactions are not accessible …

To evaluate the toxicity of atrazine on the freshwater microalgae Chlorella sp. using sensitive indices indicated by photosynthetic parameters

C Sun, Y Xu, N Hu, J Ma, S Sun, W Cao, G Klobučar… - Chemosphere, 2020 - Elsevier
Atrazine is a widely-applied herbicide used primarily to control weeds, which can persist in
the ecosystem and exert potential toxicity to phytoplankton in the aquatic environment. In this …

Evolution of new enzymes by gene duplication and divergence

SD Copley - The FEBS journal, 2020 - Wiley Online Library
Thousands of new metabolic and regulatory enzymes have evolved by gene duplication and
divergence since the dawn of life. New enzyme activities often originate from promiscuous …

Design and optimization of a cell-free atrazine biosensor

AD Silverman, U Akova, KK Alam, MC Jewett… - ACS synthetic …, 2020 - ACS Publications
Recent advances in cell-free synthetic biology have spurred the development of in vitro
molecular diagnostics that serve as effective alternatives to whole-cell biosensors. However …

Atrazine uptake, translocation, bioaccumulation and biodegradation in cattail (Typha latifolia) as a function of exposure time

DJ Pérez, WJ Doucette, MT Moore - Chemosphere, 2022 - Elsevier
The extensive use and environmental persistence of atrazine has resulted in its ubiquitous
occurrence in water resources. Some reports have described atrazine bioaccumulation and …

Recent trends using natural polymeric nanofibers as supports for enzyme immobilization and catalysis

RS Khan, AH Rather, TU Wani, S Rather… - Biotechnology and …, 2023 - Wiley Online Library
All the disciplines of science, especially biotechnology, have given continuous attention to
the area of enzyme immobilization. However, the structural support made by material …

Evolution of atrazine-degrading capabilities in the environment

N Udiković-Kolić, C Scott, F Martin-Laurent - Applied microbiology and …, 2012 - Springer
Since their first introduction in the mid 1950s, man-made s-triazine herbicides such as
atrazine have extensively been used in agriculture to control broadleaf weed growth in …

Persistence of atrazine and trifluralin in a clay loam soil undergoing different temperature and moisture conditions

IF Chowdhury, M Rohan, BJ Stodart, C Chen… - Environmental …, 2021 - Elsevier
Dissipation kinetics of atrazine and trifluralin in a clay loam soil was investigated in a
laboratory incubation experiment under different temperature and moisture conditions. The …

Evaluation of pesticide residues in fruits and vegetables from the Aegean region of Turkey and assessment of risk to consumers

D Kazar Soydan, N Turgut, M Yalçın, C Turgut… - … Science and Pollution …, 2021 - Springer
Pesticides may cause a potential risk to human health when applied in excess to control
pests, diseases, and weeds in crop fields. In the current study, conducted in the Aegean …