Lupeol and its derivatives as anticancer and anti-inflammatory agents: Molecular mechanisms and therapeutic efficacy
K Liu, X Zhang, L Xie, M Deng, H Chen, J Song… - Pharmacological …, 2021 - Elsevier
Lupeol is a natural triterpenoid that widely exists in edible fruits and vegetables, and
medicinal plants. In the last decade, a plethora of studies on the pharmacological activities …
medicinal plants. In the last decade, a plethora of studies on the pharmacological activities …
Therapeutic potential of plants and plant derived phytochemicals against acetaminophen-induced liver injury
SB Subramanya, B Venkataraman… - International journal of …, 2018 - mdpi.com
Acetaminophen (APAP), which is also known as paracetamol or N-acetyl-p-aminophenol is
a safe and potent drug for fever, pain and inflammation when used at its normal therapeutic …
a safe and potent drug for fever, pain and inflammation when used at its normal therapeutic …
Protective effect of chrysin on cyclophosphamide-induced hepatotoxicity and nephrotoxicity via the inhibition of oxidative stress, inflammation, and apoptosis
Cyclophosphamide (CYP) is a chemotherapeutic agent used in the treatment of autoimmune
disorders and malignant diseases. However, its usage is restricted due to its severe side …
disorders and malignant diseases. However, its usage is restricted due to its severe side …
Molecular pharmacology and therapeutic advances of the pentacyclic triterpene lupeol
AAM Sohag, MT Hossain, MA Rahaman, P Rahman… - Phytomedicine, 2022 - Elsevier
Background Plant triterpenoids are major sources of nutraceuticals that provide many health
benefits to humans. Lupeol is one of the pentacyclic dietary triterpenoids commonly found in …
benefits to humans. Lupeol is one of the pentacyclic dietary triterpenoids commonly found in …
[HTML][HTML] A review on hepatoprotective and immunomodulatory herbal plants
The liver is the most important organ that plays an important role in maintaining various
physiological processes in the body. Hepatitis is an inflammation of the liver and is …
physiological processes in the body. Hepatitis is an inflammation of the liver and is …
Protective effect of lupeol against lipopolysaccharide-induced neuroinflammation via the p38/c-Jun N-terminal kinase pathway in the adult mouse brain
Recent studies have demonstrated a close interaction between neuroinflammatory
responses, increased production of inflammatory mediators, and neurodegeneration …
responses, increased production of inflammatory mediators, and neurodegeneration …
Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways
Background Ischemia/reperfusion injury plays a crucial role in renal transplantation, and
represents a significant risk factor for acute renal failure and delayed graft function. The …
represents a significant risk factor for acute renal failure and delayed graft function. The …
Recent advances in tea seeds (Camellia Sinensis (L.) O. Kuntze): Active ingredients, health effects, and potential applications
S Zhou, Z Li, H Song, H Hu, S Ma, Y Tao, Z Hao… - Trends in Food Science …, 2023 - Elsevier
Background Tea seed (TS), as the mature fruit and growth source of tea plant, has been
characterized with appealing bioactive substances, remarkable health benefits and diverse …
characterized with appealing bioactive substances, remarkable health benefits and diverse …
Acetaminophen induced hepatotoxicity: An overview of the promising protective effects of natural products and herbal formulations
Background The liver plays an important role in regulating the metabolic processes and is
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …
Lupeol Treatment Attenuates activation of glial cells and oxidative-stress-mediated neuropathology in mouse model of traumatic brain injury
Traumatic brain injury (TBI) signifies a major cause of death and disability. TBI causes
central nervous system (CNS) damage under a variety of mechanisms, including protein …
central nervous system (CNS) damage under a variety of mechanisms, including protein …