Host-malaria parasite interactions and impacts on mutual evolution
X Su, C Zhang, DA Joy - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Malaria is the most deadly parasitic disease, affecting hundreds of millions of people
worldwide. Malaria parasites have been associated with their hosts for millions of years …
worldwide. Malaria parasites have been associated with their hosts for millions of years …
Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus …
Background Infections with helminths cause an enormous disease burden in billions of
animals and plants worldwide. Large scale use of anthelmintics has driven the evolution of …
animals and plants worldwide. Large scale use of anthelmintics has driven the evolution of …
Bulk segregant linkage mapping for rodent and human malaria parasites
Abstract In 2005 Richard Carter's group surprised the malaria genetics community with an
elegant approach to rapidly mapping the genetic basis of phenotypic traits in rodent malaria …
elegant approach to rapidly mapping the genetic basis of phenotypic traits in rodent malaria …
[HTML][HTML] Forward genetic analysis of monensin and diclazuril resistance in Eimeria tenella
H Zhang, L Zhang, G Ren, H Si, X Song, X Liu… - International Journal for …, 2023 - Elsevier
Worldwide distributed coccidiosis is caused by infection of both Eimeria species and
Cystoisospora in the host intestine and causes huge economic losses to the livestock …
Cystoisospora in the host intestine and causes huge economic losses to the livestock …
Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle
Determining the genetic basis of fitness is central to understanding evolution and
transmission of microbial pathogens. In human malaria parasites (Plasmodium falciparum) …
transmission of microbial pathogens. In human malaria parasites (Plasmodium falciparum) …
A Malaria Parasite Cross Reveals Genetic Determinants of Plasmodium falciparum Growth in Different Culture Media
What genes determine in vitro growth and nutrient utilization in asexual blood-stage malaria
parasites? Competition experiments between NF54, clone 3D7, a lab-adapted African …
parasites? Competition experiments between NF54, clone 3D7, a lab-adapted African …
The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice
KA Button-Simons, S Kumar, N Carmago… - Communications …, 2021 - nature.com
Genetic crosses are most powerful for linkage analysis when progeny numbers are high,
parental alleles segregate evenly and numbers of inbred progeny are minimized. We …
parental alleles segregate evenly and numbers of inbred progeny are minimized. We …
Optimizing bulk segregant analysis of drug resistance using Plasmodium falciparum genetic crosses conducted in humanized mice
Classical malaria parasite genetic crosses involve isolation, genotyping, and phenotyping of
progeny parasites, which is time consuming and laborious. We tested a rapid alternative …
progeny parasites, which is time consuming and laborious. We tested a rapid alternative …
[HTML][HTML] Genome-wide analysis of the response to ivermectin treatment by a Swedish field population of Haemonchus contortus
Haemonchus contortus is a pathogenic gastrointestinal nematode of small ruminants and, in
part due to its capacity to develop resistance to drugs, contributes to significant losses in the …
part due to its capacity to develop resistance to drugs, contributes to significant losses in the …
Genetic mapping of determinants in drug resistance, virulence, disease susceptibility, and interaction of host-rodent malaria parasites
Genetic mapping has been widely employed to search for genes linked to phenotypes/traits
of interest. Because of the ease of maintaining rodent malaria parasites in laboratory mice …
of interest. Because of the ease of maintaining rodent malaria parasites in laboratory mice …