Fungal evolution: major ecological adaptations and evolutionary transitions

MA Naranjo‐Ortiz, T Gabaldón - Biological Reviews, 2019 - Wiley Online Library
Fungi are a highly diverse group of heterotrophic eukaryotes characterized by the absence
of phagotrophy and the presence of a chitinous cell wall. While unicellular fungi are far from …

Fungal P450 monooxygenases - the diversity in catalysis and their promising roles in biocontrol activity

R Hussain, M Ahmed, TA Khan, Y Akhter - Applied microbiology and …, 2020 - Springer
The fungal P 450s catalyze vital monooxygenation reactions in primary and secondary
metabolism, which may lead to the production of diverse secondary metabolites. Many of …

Gene family expansions and transcriptome signatures uncover fungal adaptations to wood decay

H Hage, S Miyauchi, M Virágh, E Drula… - Environmental …, 2021 - Wiley Online Library
Because they comprise some of the most efficient wood‐decayers, Polyporales fungi impact
carbon cycling in forest environment. Despite continuous discoveries on the enzymatic …

Contrasting Health Effects of Bacteroidetes and Firmicutes Lies in Their Genomes: Analysis of P450s, Ferredoxins, and Secondary Metabolite Clusters

BVZ Nkosi, T Padayachee, D Gront, DR Nelson… - International journal of …, 2022 - mdpi.com
Species belonging to the bacterial phyla Bacteroidetes and Firmicutes represent over 90%
of the gastrointestinal microbiota. Changes in the ratio of these two bacterial groups were …

Fungal genomes and insights into the evolution of the kingdom

JE Stajich - Microbiology spectrum, 2017 - Am Soc Microbiol
The kingdom Fungi comprises species that inhabit nearly all ecosystems. Fungi exist as both
free-living and symbiotic unicellular and multicellular organisms with diverse morphologies …

Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s

M Parvez, LB Qhanya, NT Mthakathi… - Scientific reports, 2016 - nature.com
Since the initial identification of cytochrome P450 monooxygenases (CYPs/P450s), great
progress has been made in understanding their structure-function relationship, diversity and …

Conserved white-rot enzymatic mechanism for wood decay in the Basidiomycota genus Pycnoporus

S Miyauchi, H Hage, E Drula, L Lesage-Meessen… - DNA …, 2020 - academic.oup.com
White-rot (WR) fungi are pivotal decomposers of dead organic matter in forest ecosystems
and typically use a large array of hydrolytic and oxidative enzymes to deconstruct …

The First Whole Genome Sequencing of Sanghuangporus sanghuang Provides Insights into Its Medicinal Application and Evolution

JH Jiang, SH Wu, LW Zhou - Journal of Fungi, 2021 - mdpi.com
Sanghuangporus is a medicinal macrofungal genus typified by S. sanghuang, the very
species utilized in traditional Chinese medicines by Chinese ancient people. To facilitate the …

Latent potentials of the white-rot basidiomycete Phanerochaete chrysosporium responsible for sesquiterpene metabolism: CYP5158A1 and CYP5144C8 decorate (E) …

H Ichinose, S Ukeba, T Kitaoka - Enzyme and Microbial Technology, 2022 - Elsevier
Basidiomycetes produce various sesquiterpenoids and their relevance for pharmaceutical
and agricultural applications and understanding their biosynthetic machinery to produce …

Impact of lifestyle on cytochrome P450 monooxygenase repertoire is clearly evident in the bacterial phylum Firmicutes

T Padayachee, N Nzuza, W Chen, DR Nelson… - Scientific reports, 2020 - nature.com
Abstract Cytochrome P450 monooxygenases (CYPs/P450s), heme thiolate proteins, are
well known for their role in organisms' primary and secondary metabolism. Research on …