The act of defaecation, although a ubiquitous human experience, requires the coordinated
actions of the anorectum and colon, pelvic floor musculature, and the enteric, peripheral and …

Chronic constipation is a prevalent condition that severely impacts the quality of life of those
affected. Several types of primary chronic constipation, which show substantial overlap …

Our understanding of human colonic motility, and autonomic reflexes that generate motor
patterns, has increased markedly through high-resolution manometry. Details of the motor …

Background Until recently, investigations of the normal patterns of motility of the healthy
human colon have been limited by the resolution of in vivo recording techniques. Methods …

The fundamental gastrointestinal functions include motility, sensation, absorption, secretion,
digestion, and intestinal barrier function. Digestion of food and absorption of nutrients …

Human defecation involves integrated and coordinated sensorimotor functions, orchestrated
by central, spinal, peripheral (somatic and visceral), and enteric neural activities, acting on a …

Postoperative ileus (POI) is an abnormal pattern of gastrointestinal motility characterized by
nausea, vomiting, abdominal distension and/or delayed passage of flatus or stool, which …

In recent years there have been significant technical and methodological advances in our
ability to record the movements of the gastrointestinal tract. This has led to significant …

Background The wireless motility capsule (WMC) offers the ability to investigate luminal
gastrointestinal (GI) physiology in a minimally invasive manner. Aim To investigate the effect …

We aimed to determine whether rectal distension and/or infusion of bile acids stimulates
propagating or nonpropagating activity in the unprepared proximal colon in 10 healthy …