Although available data are still limited, real-world evidence regarding mainly ceftolozane-
tazobactam and ceftazidime-avibactam could support the administration of novel beta …

Introduction Several novel beta-lactams (BLs) and/or beta lactams/beta-lactamase inhibitors
(BL/BLIs) have been recently developed for the management of multidrug-resistant bacterial …

Outpatient parenteral antimicrobial therapy (OPAThttp) programs have become an important
healthcare tool around the world. Portable elastomeric infusion pumps are functional …

Temocillin is an old antibiotic, but given its particular characteristics, it may be a suitable
alternative to carbapenems for treating infections due to ESBL-producing Enterobacterales …

Purpose Although outpatient parenteral antibiotic therapy (OPAT) can be a good approach
to treatment of infections, a lack of data regarding antibiotic stability in portable elastomeric …

Consolidated data from pharmacokinetic and pharmacodynamic studies support the
administration of β-lactam antibiotics in prolonged infusion (ie, extended or continuous) to …

Outpatient parenteral antimicrobial therapy (OPAT) programs encompass a range of
healthcare processes aiming to treat infections at home, with the preferential use of the …

Outpatient parenteral antimicrobial therapy (OPAT) is a useful treatment strategy against
Pseudomonas aeruginosa and other multidrug-resistant bacteria. However, it is hindered by …

Objectives To investigate the stability of ceftolozane/tazobactam 5 mg/mL and 20 mg/mL
solutions for infusion in two elastomeric devices: FOLFusor LV10 (Baxter Healthcare) and …

Currently, ampicillin plus ceftriaxone (AC) is one of the preferred treatments for
Enterococcus faecalis infective endocarditis. However, there is a lack of stability data for the …