Advances in xanthan gum-based systems for the delivery of therapeutic agents
In the last three decades, polymers have contributed significantly to the improvement of drug
delivery technologies by enabling the controlled and sustained release of therapeutic …
delivery technologies by enabling the controlled and sustained release of therapeutic …
How can clinical safety and efficacy concerns in stem cell therapy for spinal cord injury be overcome?
Introduction Spinal cord injury (SCI) can lead to severe neurological dysfunction. Despite
scientific and medical advances, clinically effective regenerative therapies including stem …
scientific and medical advances, clinically effective regenerative therapies including stem …
The knowns and unknowns of cardiac autoimmunity in viral myocarditis
Myocarditis can result from various infectious and non‐infectious causes that can lead to
dilated cardiomyopathy (DCM) and heart failure. Among the infectious causes, viruses are …
dilated cardiomyopathy (DCM) and heart failure. Among the infectious causes, viruses are …
Analytical performance specifications for measurement uncertainty in therapeutic monitoring of immunosuppressive drugs
D Cattaneo, M Panteghini - Clinical Chemistry and Laboratory …, 2024 - degruyter.com
The measurement uncertainty (MU) estimates and the definition of its maximum allowable
limits for the clinical application of measurements represents one of the mainstays to …
limits for the clinical application of measurements represents one of the mainstays to …
Molecular Mechanisms Responsible for the Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Lung Fibrosis
CR Harrell, V Djonov, A Volarevic… - International journal of …, 2024 - mdpi.com
Mesenchymal stem cell-derived exosomes (MSC-Exos) are nano-sized extracellular
vesicles which contain various MSC-sourced anti-fibrotic, immunoregulatory and angio …
vesicles which contain various MSC-sourced anti-fibrotic, immunoregulatory and angio …
Immunosuppressive strategies in face and hand transplantation: A comprehensive systematic review of current therapy regimens and outcomes
L Huelsboemer, S Boroumand, A Kochen… - Frontiers in …, 2024 - frontiersin.org
Background Recipients of Vascularized Composite Allotransplants require effective
immunosuppressive therapy to prevent graft rejection. This systematic review summarizes …
immunosuppressive therapy to prevent graft rejection. This systematic review summarizes …
Immune modulation in transplant medicine: a comprehensive review of cell therapy applications and future directions
Balancing the immune response after solid organ transplantation (SOT) and vascularized
composite allotransplantation (VCA) remains an ongoing clinical challenge. While …
composite allotransplantation (VCA) remains an ongoing clinical challenge. While …
New approach methodologies to enhance human health risk assessment of immunotoxic properties of chemicals—a PARC (Partnership for the Assessment of Risk …
As a complex system governing and interconnecting numerous functions within the human
body, the immune system is unsurprisingly susceptible to the impact of toxic chemicals …
body, the immune system is unsurprisingly susceptible to the impact of toxic chemicals …
The Effects of Chronic Immunosuppressive Treatment on Morphological Changes in Cardiac Tissue and the Balance between Matrix Metalloproteinases (MMP-2 and …
A Surówka, M Żołnierczuk, P Prowans… - International Journal of …, 2024 - mdpi.com
Using different three-drug immunosuppressive treatment regimens in a rat model, we aimed
to determine the effects of long-term therapy on metalloproteinase-2 and metalloproteinase …
to determine the effects of long-term therapy on metalloproteinase-2 and metalloproteinase …
Approaches Towards Better Immunosuppressive Agents
J Walczak, D Iwaszkiewicz-Grześ… - Current Topics in …, 2024 - ingentaconnect.com
Several classes of compounds are applied in clinics due to their immunosuppressive
properties in transplantology and the treatment of autoimmune diseases. Derivatives of …
properties in transplantology and the treatment of autoimmune diseases. Derivatives of …