Placentation is a key and tightly regulated process that ensures the normal development of
the placenta and fetal growth. Preeclampsia (PE) is a hypertensive pregnancy-related …

Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …

The prevalence of the metabolic syndrome, a cluster of cardiovascular risk factors
associated with obesity and insulin resistance, is dramatically increasing in Western and …

Catalase (CAT) is a well-studied enzyme that plays an important role in protecting cells
against the toxic effects of hydrogen peroxide. In human, it has been implicated in different …

This review examines the shared immune-inflammatory, oxidative and nitrosative stress
(IO&NS) and metabolic pathways underpinning metabolic syndrome (MetS), bipolar disorder …

Background Hypertension is a major contributing factor to cardiovascular disease and is a
leading cause of death in the world. The association between hepatic enzymes and …

Vascular biology, endothelial and vascular smooth muscle and cardiac dysfunction play a
primary role in the initiation and perpetuation of hypertension, cardiovascular disease and …

Mammalian thioredoxin reductase (TrxR) is a selenoprotein with three existing isoenzymes
(TrxR1, TrxR2, and TrxR3), which is found primarily intracellularly but also in extracellular …

According to the World Health Organization (WHO), the global nutrition report shows that
whilst part of the world's population starves, the other part suffers from obesity and …

More than 60 years ago, Dr. Irvine Page proposed the Mosaic Theory of hypertension, which
states that many factors, including genetics, environment, adaptive, neural, mechanical, and …