Immune dysregulation in autism spectrum disorder: what do we know about it?

MA Robinson-Agramonte, E Noris García… - International journal of …, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a group of complex multifactorial neurodevelopmental
disorders characterized by a wide and variable set of neuropsychiatric symptoms, including …

The immune system, cytokines, and biomarkers in autism spectrum disorder

A Masi, N Glozier, R Dale, AJ Guastella - Neuroscience bulletin, 2017 - Springer
Abstract Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental condition
characterized by variable impairments in communication and social interaction as well as …

Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders

M Fiorentino, A Sapone, S Senger, SS Camhi… - Molecular autism, 2016 - Springer
Background Autism spectrum disorders (ASD) are complex conditions whose pathogenesis
may be attributed to gene–environment interactions. There are no definitive mechanisms …

Characterizing the interplay between autism spectrum disorder and comorbid medical conditions: An integrative review

C Tye, AK Runicles, AJO Whitehouse… - Frontiers in …, 2019 - frontiersin.org
Co-occurring medical disorders and associated physiological abnormalities in individuals
with autism spectrum disorder (ASD) may provide insight into causal pathways or underlying …

Microglial contribution to the pathology of neurodevelopmental disorders in humans

R Matuleviciute, ET Akinluyi, TAO Muntslag… - Acta …, 2023 - Springer
Microglia are the brain's resident macrophages, which guide various developmental
processes crucial for brain maturation, activity, and plasticity. Microglial progenitors enter the …

Evidence supporting an altered immune response in ASD

J Mead, P Ashwood - Immunology letters, 2015 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by
deficits in social interactions, communication, and increased stereotypical repetitive …

Immune abnormalities in autism spectrum disorder—could they hold promise for causative treatment?

D Gładysz, A Krzywdzińska, KK Hozyasz - Molecular neurobiology, 2018 - Springer
Autism spectrum disorders (ASD) are characterized by impairments in language and
communication development, social behavior, and the occurrence of stereotypic patterns of …

Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers-pre-clinical and clinical investigations

J Prata, SG Santos, MI Almeida, R Coelho… - Journal of …, 2017 - Springer
In recent years, evidence supporting a link between inflammation and neuropsychiatric
disorders has been mounting. Autism spectrum disorders (ASD) and schizophrenia share …

Immunological dysfunction in autism spectrum disorder: a potential target for therapy

J Marchezan, EGA Winkler dos Santos… - …, 2019 - karger.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with an
unknown etiology and currently few effective therapies. Immune system alterations have …

Anti-inflammatory cytokines in autism spectrum disorders: A systematic review and meta-analysis

A Saghazadeh, B Ataeinia, K Keynejad… - Cytokine, 2019 - Elsevier
Background In the search for the causes of autism spectrum disorders (ASD), inflammatory
markers have emerged as potential candidates. The present meta-analysis was performed …