The role of endothelin-1 and endothelin receptor antagonists in inflammatory response and sepsis
A Kowalczyk, P Kleniewska, M Kolodziejczyk… - Archivum immunologiae …, 2015 - Springer
Abstract Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor, mainly secreted by
endothelial cells. It acts through two types of receptors: ETA and ETB. Apart from a …
endothelial cells. It acts through two types of receptors: ETA and ETB. Apart from a …
Endothelin-1 axes in the framework of predictive, preventive and personalised (3P) medicine
A Torres Crigna, B Link, M Samec, FA Giordano… - EPMA Journal, 2021 - Springer
Abstract Endothelin-1 (ET-1) is involved in the regulation of a myriad of processes highly
relevant for physical and mental well-being; female and male health; in the modulation of …
relevant for physical and mental well-being; female and male health; in the modulation of …
[HTML][HTML] Selenomethionine supplementation reduces lesion burden, improves vessel function and modulates the inflammatory response within the setting of …
Y Zhang, SP Cartland, R Henriquez, S Patel… - Redox biology, 2020 - Elsevier
Atherosclerosis is a chronic inflammatory disease of the vasculature characterised by the
infiltration of activated neutrophils and macrophages at sites of damage within the vessel …
infiltration of activated neutrophils and macrophages at sites of damage within the vessel …
Association between ambient particulate air pollution and soluble biomarkers of endothelial function: a meta-analysis
K Wang, L Lei, G Li, Y Lan, W Wang, J Zhu, Q Liu… - Toxics, 2024 - mdpi.com
Background: The burden of cardiovascular diseases caused by ambient particulate air
pollution is universal. An increasing number of studies have investigated the potential effects …
pollution is universal. An increasing number of studies have investigated the potential effects …
Vascular smooth muscle cell peroxisome proliferator-activated receptor γ protects against endothelin-1-induced oxidative stress and inflammation
N Idris-Khodja, S Ouerd, M Trindade… - Journal of …, 2017 - journals.lww.com
Aims: Peroxisome proliferator-activated receptor γ (PPARγ) agonists reduce blood pressure
and vascular injury in hypertensive rodents. Pparγ inactivation in vascular smooth muscle …
and vascular injury in hypertensive rodents. Pparγ inactivation in vascular smooth muscle …
Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral …
P Sfyri, A Matsakas - Journal of biomedical science, 2017 - Springer
Atherosclerosis is a chronic inflammatory process that, in the presence of hyperlipidaemia,
promotes the formation of atheromatous plaques in large vessels of the cardiovascular …
promotes the formation of atheromatous plaques in large vessels of the cardiovascular …
Potential roles of endoplasmic reticulum stress and cellular proteins implicated in diabesity
S Mustapha, M Mohammed, AK Azemi… - Oxidative medicine …, 2021 - Wiley Online Library
The role of the endoplasmic reticulum (ER) has evolved from protein synthesis, processing,
and other secretory pathways to forming a foundation for lipid biosynthesis and other …
and other secretory pathways to forming a foundation for lipid biosynthesis and other …
Digestive n‐6 lipid oxidation, a key trigger of vascular dysfunction and atherosclerosis in the Western diet: Protective effects of apple polyphenols
G Bolea, C Philouze, M Dubois… - Molecular Nutrition & …, 2021 - Wiley Online Library
Scope A main risk factor of atherosclerosis is a Western diet (WD) rich in n‐6
polyunsaturated fatty acids (PUFAs) sensitive to oxidation. Their oxidation can be initiated by …
polyunsaturated fatty acids (PUFAs) sensitive to oxidation. Their oxidation can be initiated by …
Chronic elevation of endothelin-1 alone may not be sufficient to impair endothelium-dependent relaxation
ZI Grunewald, TJ Jurrissen, ML Woodford… - …, 2019 - Am Heart Assoc
Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide considered to be causally
implicated in hypertension and the development of cardiovascular disease. Increased ET-1 …
implicated in hypertension and the development of cardiovascular disease. Increased ET-1 …
Effects of coal-fired PM2.5 on the expression levels of atherosclerosis-related proteins and the phosphorylation level of MAPK in ApoE−/− mice
Background Air pollution increases the morbidity and mortality of cardiovascular disease
(CVD). Atherosclerosis (AS) is the pathological basis of most CVD, and the progression of …
(CVD). Atherosclerosis (AS) is the pathological basis of most CVD, and the progression of …