Vascular endothelial growth factor receptors (VEGFRs) are a family of receptor protein
tyrosine kinases that play an important role in the regulation of tumor-induced angiogenesis …

Macrophages are a specialized class of innate immune cells with multifaceted roles in
modulation of the inflammatory response, homeostasis, and wound healing. While …

Immune checkpoint blockade therapy has demonstrated promising clinical outcomes for
multiple cancer types. However, the emergence of resistance as well as inadequate …

Novel treatment approaches are needed to overcome innate and acquired mechanisms of
resistance to current anticancer therapies in cancer cells and the tumour immune …

Macrophages are one of the most abundant non‐malignant cells in the tumor
microenvironment, playing critical roles in mediating tumor immunity. As important innate …

Neutrophils have been extensively described in the pathophysiology of autoimmune and
infectious diseases. Accumulating evidence also suggests the important role of neutrophils …

Protein kinases have grown over the past few years as a crucial target for different cancer
types. With the multifactorial nature of cancer, and the fast development of drug resistance …

Efferocytosis of apoptotic cancer cells by tumor-associated macrophages or other
phagocytes is reported to promote tumor immunosuppression by preventing them from …

Metastasis is the leading cause of cancer‐associated death, with poor prognosis even after
extensive treatment. The dormancy of metastatic cancer cells during dissemination or after …

Receptor tyrosine kinases have been shown to dysregulate a number of pathways
associated with tumor development, progression, and metastasis. Axl is a receptor tyrosine …