Iron is essential for the function of all cells through its roles in oxygen delivery, electron
transport, and enzymatic activity. Cells with high metabolic rates require more iron and are at …

This is the fifth in the series of reviews developed as part of the Biomarkers of Nutrition for
Development (BOND) program. The BOND Iron Expert Panel (I-EP) reviewed the extant …

There is increasing evidence from preclinical and human studies that nutrition in the late
foetal and early neonatal period has a significant impact on neurodevelopment across the …

Iron deficiency is the most common micronutrient deficiency in the world and
disproportionately affects pregnant women and young children. Iron deficiency has negative …

During restricted time windows of postnatal life, called critical periods, neural circuits are
highly plastic and are shaped by environmental stimuli. In several mammalian brain areas …

Iron deficiency (ID) before the age of 3 y can lead to long-term neurological deficits despite
prompt diagnosis of ID anemia (IDA) by screening of hemoglobin concentrations followed by …

The human brain undergoes a remarkable transformation during fetal life and the first
postnatal years from a relatively undifferentiated but pluripotent organ to a highly specified …

Objective: To consider the key implications of iron deficiency for biochemical and
physiological functions beyond erythropoiesis. Methods: PubMed was searched for relevant …

The role of iron in neurodevelopment has long been recognized, and the adverse effects of
early‐life iron deficiency on brain development and subsequent function across the lifespan …

Disrupted brain iron homeostasis is a common feature of neurodegenerative disease. To
begin to understand how neuronal iron handling might be involved, we focused on …