Circadian rhythms and cancers: the intrinsic links and therapeutic potentials

L Zhou, Z Zhang, E Nice, C Huang, W Zhang… - Journal of Hematology & …, 2022 - Springer
The circadian rhythm is an evolutionarily conserved time-keeping system that comprises a
wide variety of processes including sleep–wake cycles, eating–fasting cycles, and activity …

Endocrine crosstalk between skeletal muscle and the brain

J Delezie, C Handschin - Frontiers in neurology, 2018 - frontiersin.org
Skeletal muscle is an essential regulator of energy homeostasis and a potent coordinator of
exercise-induced adaptations in other organs including the liver, fat or the brain. Skeletal …

A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription

L Jin, Q Tang, S Hu, Z Chen, X Zhou, B Zeng… - Nature …, 2021 - nature.com
A comprehensive transcriptomic survey of pigs can provide a mechanistic understanding of
tissue specialization processes underlying economically valuable traits and accelerate their …

Exercise-released myokines in the control of energy metabolism

C Laurens, A Bergouignan, C Moro - Frontiers in physiology, 2020 - frontiersin.org
Physical activity reduces cardiometabolic risk, while physical inactivity increases chronic
diseases risk. This led to the idea that exercise-induced muscle contraction contributes to …

Myokines in skeletal muscle physiology and metabolism: Recent advances and future perspectives

DK Das, ZA Graham, CP Cardozo - Acta Physiologica, 2020 - Wiley Online Library
Myokines are molecules produced and secreted by skeletal muscle to act in an auto‐, para‐
and endocrine manner to alter physiological function of target tissues. The growing number …

Interactions between muscle and bone—where physics meets biology

M Herrmann, K Engelke, R Ebert, S Müller-Deubert… - Biomolecules, 2020 - mdpi.com
Muscle and bone interact via physical forces and secreted osteokines and myokines.
Physical forces are generated through gravity, locomotion, exercise, and external devices …

Cytokines and exosomal miRNAs in skeletal muscle–adipose crosstalk

L Guo, M Quan, W Pang, Y Yin, F Li - Trends in Endocrinology & …, 2023 - cell.com
Skeletal muscle and adipose tissues (ATs) are secretory organs that release secretory
factors including cytokines and exosomes. These factors mediate muscle–adipose crosstalk …

[HTML][HTML] State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions

KM Lavin, PM Coen, LC Baptista, MB Bell… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Exercise-induced myokines can explain the importance of physical activity in the elderly: an overview

JH Kwon, KM Moon, KW Min - Healthcare, 2020 - mdpi.com
Physical activity has been found to aid the maintenance of health in the elderly. Exercise-
induced skeletal muscle contractions lead to the production and secretion of many small …

Extracellular vesicles: delivery vehicles of myokines

E Trovato, V Di Felice, R Barone - Frontiers in physiology, 2019 - frontiersin.org
Movement and regular physical activity are two important factors that help the human body
prevent, reduce and treat different chronic diseases such as obesity, type 2 diabetes, heart …