The Research Domain Criteria (RDoC) address three types of aggression: frustrative non‐
reward, defensive aggression and offensive/proactive aggression. This review sought to …

Background Bipolar disorder (BD) is a common affective disorder characterized by recurrent
oscillations between mood states and associated with inflammatory diseases and chronic …

Controlling aggression is a crucial skill in social species like rodents and humans and has
been associated with anterior cingulate cortex (ACC). Here, we directly link the failed …

Background Systemic inflammation-immune dysregulation and brain abnormalities are
believed to contribute to the pathogenesis of bipolar disorder (BD). However, the …

Humans are ubiquitously exposed to neurotoxicants in air pollution, causing increased risk
for psychiatric outcomes. Effects of prenatal exposure to air pollution on early emerging …

Stressful events have been implicated in the evolution of mood disorders. In addition to brain
neurotransmitters and growth factors, the view has been offered that these disorders might …

Inflammation and abnormalities in Toll-like receptor (TLR) expression and activation have
been linked to major depressive disorder (MDD). However, negative regulators of TLR …

Aggressive behavior (AB) represents a public health concern often associated with severe
psychiatric disorders. Although most psychiatric patients are not aggressive, untreated …

Human aggression is a complex and widespread social behavior that is overrepresented in
individuals affected by severe mental illness (SMI), such as schizophrenia (SCZ), bipolar …

To find biomarkers to assess the risk of aggression, we looked at the association between
aggression and levels of body inflammation in patients with schizophrenia. The Modified …