Therapeutic viral gene delivery is an emerging technology which aims to correct genetic
mutations by introducing new genetic information to cells either to correct a faulty gene or to …

Gene therapy, which aims to cure diseases by knocking out, editing, correcting or
compensating abnormal genes, provides new strategies for the treatment of tumors, genetic …

Cell-penetrating peptides (CPPs), as non-viral gene delivery vectors, are considered with
lower immunogenic response, and safer and higher gene capacity than viral systems. In our …

The utilization of nanoparticles for the intracellular delivery of theranostic agents faces one
substantial limitation. Sequestration in intracellular vesicles prevents them from reaching the …

Abstract Background Adeno‐associated viruses (AAVs) are gaining interest in the
development of cellular immunotherapy. Compared to other viral vectors, AAVs can reduce …

In this chapter, the delivery of biomolecules such as oligonucleotides, proteins, peptides and
others by connection of the power of modern nanoparticles with the flexibility and efficacy of …

Extension of longevity is no longer a science fiction and has been in progress of becoming
scientifically achievable. The focus of current anti-aging strategies has shifted from geriatrics …

Interleukin 15 má velký potenciál pro využití například v biologické léčbě nádorových
onemocnění. Je zapojen do celé řady imunitních procesů, kde mezi nejdůležitější z nich …