[HTML][HTML] Prokaryote pangenomes are dynamic entities

EA Cummins, RJ Hall, JO McInerney… - Current Opinion in …, 2022 - Elsevier
Prokaryote pangenomes are influenced heavily by environmental factors and the
opportunity for gene gain and loss events. As the field of pangenome analysis has …

[HTML][HTML] Metaphenotypes associated with recurrent genomic lineages of Campylobacter jejuni responsible for human infections in Luxembourg

M Nennig, A Clément, E Longueval… - Frontiers in …, 2022 - frontiersin.org
Campylobacter jejuni is a leading cause of foodborne illnesses worldwide. Although
considered fragile, this microaerophilic bacterium is able to survive in various challenging …

Five centuries of genome evolution and multi-host adaptation of Campylobacter jejuni in Brazil

ABG Buiatte, SSR Souza, LRM Costa… - Microbial …, 2024 - microbiologyresearch.org
Consumption of raw, undercooked or contaminated animal food products is a frequent
cause of Campylobacter jejuni infection. Brazil is the world's third largest producer and a …

Genetic diversity and variation in antimicrobial-resistance determinants of non-serotype 2 Streptococcus suis isolates from healthy pigs

N Kittiwan, JK Calland, E Mourkas… - Microbial …, 2022 - microbiologyresearch.org
Streptococcus suis is a leading cause of bacterial meningitis in South-East Asia, with
frequent zoonotic transfer to humans associated with close contact with pigs. A small …

Detecting co-selection through excess linkage disequilibrium in bacterial genomes

S Mallawaarachchi, G Tonkin-Hill… - NAR Genomics and …, 2024 - academic.oup.com
Population genomics has revolutionized our ability to study bacterial evolution by enabling
data-driven discovery of the genetic architecture of trait variation. Genome-wide association …

Genomic tailoring of autogenous poultry vaccines to reduce Campylobacter from farm to fork

JK Calland, ME Pesonen, J Mehat, B Pascoe… - npj Vaccines, 2024 - nature.com
Campylobacter is a leading cause of food-borne gastroenteritis worldwide, linked to the
consumption of contaminated poultry meat. Targeting this pathogen at source, vaccines for …

Dynamics of bacterial recombination in the human gut microbiome

Z Liu, BH Good - Plos Biology, 2024 - journals.plos.org
Horizontal gene transfer (HGT) is a ubiquitous force in microbial evolution. Previous work
has shown that the human gut is a hotspot for gene transfer between species, but the more …

Epistasis, core-genome disharmony, and adaptation in recombining bacteria

AJ Taylor, K Yahara, B Pascoe, S Ko, L Mageiros… - Mbio, 2024 - Am Soc Microbiol
Recombination of short DNA fragments via horizontal gene transfer (HGT) can introduce
beneficial alleles, create genomic disharmony through negative epistasis, and create …

Emerging patterns of fluoroquinolone resistance in Campylobacter jejuni in the UK [1998–2018]

D Veltcheva, FM Colles, M Varga… - Microbial …, 2022 - microbiologyresearch.org
Campylobacter jejuni (C. jejuni) is the most common causative agent of bacterial food
poisoning worldwide and is known to be genetically highly diverse. C. jejuni is increasingly …

Evidence of potential Campylobacter jejuni zooanthroponosis in captive macaque populations

X Zang, B Pascoe, E Mourkas, K Kong… - Microbial …, 2023 - microbiologyresearch.org
Non-human primates share recent common ancestry with humans and exhibit comparable
disease symptoms. Here, we explored the transmission potential of enteric bacterial …