Pulmonary drug delivery by powder aerosols
MY Yang, JGY Chan, HK Chan - Journal of Controlled Release, 2014 - Elsevier
The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …
Fibrosis imaging: current concepts and future directions
Fibrosis plays an important role in many different pathologies. It results from tissue injury,
chronic inflammation, autoimmune reactions and genetic alterations, and it is characterized …
chronic inflammation, autoimmune reactions and genetic alterations, and it is characterized …
Optimized 3D ultrashort echo time pulmonary MRI
Purpose To optimize 3D radial ultrashort echo time MRI for high resolution whole‐lung
imaging. Methods 3D radial ultrashort echo time was implemented on a 3T scanner to …
imaging. Methods 3D radial ultrashort echo time was implemented on a 3T scanner to …
MRI of the lung (3/3)—current applications and future perspectives
J Biederer, S Mirsadraee, M Beer, F Molinari… - Insights into …, 2012 - Springer
Background MRI of the lung is recommended in a number of clinical indications. Having a
non-radiation alternative is particularly attractive in children and young subjects, or pregnant …
non-radiation alternative is particularly attractive in children and young subjects, or pregnant …
Short-T2 MRI: Principles and recent advances
M Weiger, KP Pruessmann - Progress in nuclear magnetic resonance …, 2019 - Elsevier
Among current modalities of biomedical and diagnostic imaging, MRI stands out by virtue of
its versatile contrast obtained without ionizing radiation. However, in various cases, eg …
its versatile contrast obtained without ionizing radiation. However, in various cases, eg …
The gravitational distribution of ventilation-perfusion ratio is more uniform in prone than supine posture in the normal human lung
AC Henderson, RC Sá, RJ Theilmann… - Journal of applied …, 2013 - journals.physiology.org
The gravitational gradient of intrapleural pressure is suggested to be less in prone posture
than supine. Thus the gravitational distribution of ventilation is expected to be more uniform …
than supine. Thus the gravitational distribution of ventilation is expected to be more uniform …
Hyperpolarized 129Xe MR Imaging of Alveolar Gas Uptake in Humans
ZI Cleveland, GP Cofer, G Metz, D Beaver, J Nouls… - PloS one, 2010 - journals.plos.org
Background One of the central physiological functions of the lungs is to transfer inhaled
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …
Quantitative analysis of hyperpolarized 129Xe gas transfer MRI
Purpose Hyperpolarized 129Xe magnetic resonance imaging (MRI) using Dixon‐based
decomposition enables single‐breath imaging of 129Xe in the airspaces, interstitial barrier …
decomposition enables single‐breath imaging of 129Xe in the airspaces, interstitial barrier …
Retrospective respiratory self‐gating and removal of bulk motion in pulmonary UTE MRI of neonates and adults
Purpose To implement pulmonary three‐dimensional (3D) radial ultrashort echo‐time (UTE)
MRI in non‐sedated, free‐breathing neonates and adults with retrospective motion tracking …
MRI in non‐sedated, free‐breathing neonates and adults with retrospective motion tracking …
Early diagnosis and real-time monitoring of regional lung function changes to prevent chronic obstructive pulmonary disease progression to severe emphysema
T Jung, N Vij - Journal of Clinical Medicine, 2021 - mdpi.com
First-and second-hand exposure to smoke or air pollutants is the primary cause of chronic
obstructive pulmonary disease (COPD) pathogenesis, where genetic and age-related …
obstructive pulmonary disease (COPD) pathogenesis, where genetic and age-related …