[HTML][HTML] Striatin family proteins: the neglected scaffolds

GK Tanti, P Pandey, S Shreya, BP Jain - Biochimica et Biophysica Acta …, 2023 - Elsevier
The Striatin family of proteins constitutes Striatin, SG2NA, and Zinedin. Members of this
family of proteins act as a signaling scaffold due to the presence of multiple protein-protein …

High STRN expression promotes HCC invasion and migration but not cell proliferation or apoptosis through facilitating epithelial‐mesenchymal transition

Q Du, J Yao, Y Zhou, L Xu, F Zhao… - BioMed Research …, 2020 - Wiley Online Library
A STRN-ALK fusion protein has been recently identified as a potential therapeutic target in
multiple cancers; however, the role of STRN alone in regulating the biological function of …

The profile of expression of the scaffold protein SG2NA (s) differs between cancer types and its interactome in normal vis-a-vis breast tumor tissues suggests its wide …

P Bisoyi, P Devi, K Besra, A Prasad, BP Jain… - Molecular and Cellular …, 2022 - Springer
Striatin and SG2NA are scaffold proteins that form signaling complexes called STRIPAK. It
has been associated with developmental abnormalities, cancer, and several other diseases …

[HTML][HTML] Altered expression of striatin‑4 is associated with poor prognosis in bladder transitional cell carcinoma

Y Zhang, X Gu, F Jiang, P Sun, X Li - Oncology Letters, 2021 - spandidos-publications.com
Abstract Striatin‑4 (STRN4 or Zinedin) is a scaffolding protein belonging to the mammalian
STRN family of proteins and consists of multiple functional signaling domains. Due to its …

Ectopic expression of 35 kDa and knocking down of 78 kDa SG2NAs induce cytoskeletal reorganization, alter membrane sialylation, and modulate the markers of EMT

R Gupta, G Kumar, BP Jain, S Chandra… - Molecular and Cellular …, 2021 - Springer
SG2NA is a protein of the striatin family that organizes STRIPAK complexes. It has splice
variants expressing differentially in tissues. Its 78 kDa isoform regulates cell cycle, maintains …

Subcellular dynamics of variants of SG2NA in NIH3T3 fibroblasts

P Chauhan, R Gupta, BP Jain, S Pandey… - Cell Biology …, 2020 - Wiley Online Library
Abstract SG2NA, a WD40 repeat protein of the Striatin subfamily, has four splicing and one
messenger RNA edit variants. It is fast emerging as a scaffold for multimeric signaling …

Bases moleculares de la interacción, de proteínas de transporte vesicular

D Lopez Martinez - … con membranas: proteínas quinasas cy rabfilina …, 2022 - digitum.um.es
Las vesículas intracelulares se transportan de un orgánulo a otro en respuesta a distintos
estímulos. La dirección y eficacia de la entrega de vesículas hasta su membrana de destino …