When smartphone enters food safety: A review in on-site analysis for foodborne pathogens using smartphone-assisted biosensors

T Yang, Z Luo, T Bewal, L Li, Y Xu, SM Jafari, X Lin - Food Chemistry, 2022 - Elsevier
Pathogens are one of the supreme threats for the public health around the world in food
supply chain. The on-site monitoring is an emerging trend for screening pathogens during …

[HTML][HTML] Linker-mediated oriented antibody immobilisation strategies for a more efficient immunosensor and diagnostic applications: A review

SY Gan, GJ Tye, AL Chew, WK Ng, NS Lai - Biosensors and Bioelectronics …, 2023 - Elsevier
The conjugation of antibodies onto the solid surface in a well-oriented manner has a
profound impact on the sensitivity and limit of detection of an immunoassay. The chosen …

Surface passivation with a perfluoroalkane brush improves the precision of single-molecule measurements

CJ Bueno-Alejo, M Santana Vega… - … Applied Materials & …, 2022 - ACS Publications
Single-molecule imaging is invaluable for investigating the heterogeneous behavior and
interactions of biological molecules. However, an impediment to precise sampling of single …

Comparison of oriented and non-oriented antibody conjugation with AIE fluorescence microsphere for the immunochromatographic detection of enrofloxacin

L Hu, Z Chen, T Li, X Ye, Q Luo, W Lai - Food Chemistry, 2023 - Elsevier
Antibodies and labels were typically non-oriented conjugated in conventional
immunochromatographic assays (ICAs). In this work, a C-terminal cysteine-tagged …

Magnetic separation of antibodies with high binding capacity by site-directed immobilization of protein A-domains to bare iron oxide nanoparticles

Y Kaveh-Baghbaderani, R Allgayer… - ACS Applied Nano …, 2021 - ACS Publications
The demand for purified antibodies is ever-rising. This study presents a nanoparticle-based
material for efficient magnetic separation of immunoglobulin G (IgG) with high binding …

Profiling the biophysical developability properties of common IgG1 Fc effector silencing variants

R Pejchal, AB Cooper, ME Brown, M Vásquez… - Antibodies, 2023 - mdpi.com
Therapeutic antibodies represent the most significant modality in biologics, with around 150
approved drugs on the market. In addition to specific target binding mediated by the variable …

Characterization of FcγRIa (CD64) as a ligand molecule for site-specific IgG1 capture: a side-by-side Comparison with protein A

E Capkin, H Kurt, B Gurel, D Bicak, S Akgun Bas… - Langmuir, 2022 - ACS Publications
Fc γ receptors (FcγRs) are one of the structures that can initiate effector function for
monoclonal antibodies. FcγRIa has the highest affinity toward IgG1-type monoclonal …

Selective and high-capacity binding of immunoglobulin G to zirconia nanoparticles modified with phosphate groups

A Hirano, S Kanoh, K Shiraki, M Wada… - Colloids and Surfaces B …, 2023 - Elsevier
High-performance and cost-effective purification is necessary for the development of
antibody drugs. This study found that nanoparticles of zirconia modified with phosphate …

Staphylococcal protein A-modified hydrogel facilitates in situ immunomodulation by capturing anti-HMGB1 for islet grafts

X Bai, D Wang, B Wang, X Zhang, Y Bai, X Zhang… - Acta Biomaterialia, 2023 - Elsevier
Islet transplantation is regarded as the most promising therapy for type 1 diabetes. However,
both hypoxia and immune attack impair the grafted islets after transplantation, eventually …

Magnetic nanoparticles for protein separation and purification

V Vedarethinam, J Jeevanandam, C Acquah… - … : Methods and Protocols, 2023 - Springer
Proteins are essential for various functions such as brain activity and muscle contraction in
humans. Even though food is a source of proteins, the bioavailability of proteins in most …