Optimization of nanostructured lipid carriers: Understanding the types, designs, and parameters in the process of formulations

B Subramaniam, ZH Siddik, NH Nagoor - Journal of nanoparticle research, 2020 - Springer
Lipid-based nanoparticles for drug delivery have been employed in the development of
nanomedicine for various applications. One such versatile nanoparticle type is …

A review of the structure, preparation, and application of NLCs, PNPs, and PLNs

Q Li, T Cai, Y Huang, X Xia, SPC Cole, Y Cai - Nanomaterials, 2017 - mdpi.com
Nanostructured lipid carriers (NLCs) are modified solid lipid nanoparticles (SLNs) that retain
the characteristics of the SLN, improve drug stability and loading capacity, and prevent drug …

Nanodrug delivery in reversing multidrug resistance in cancer cells

S Kapse-Mistry, T Govender, R Srivastava… - Frontiers in …, 2014 - frontiersin.org
Different mechanisms in cancer cells become resistant to one or more chemotherapeutics is
known as multidrug resistance (MDR) which hinders chemotherapy efficacy. Potential …

Brain delivery of curcumin using solid lipid nanoparticles and nanostructured lipid carriers: Preparation, optimization, and pharmacokinetic evaluation

S Sadegh Malvajerd, A Azadi, Z Izadi… - ACS chemical …, 2018 - ACS Publications
Curcumin is a multitherapeutic agent with great therapeutic potential in central nervous
system (CNS) diseases. In the current study, curcumin was encapsulated in solid lipid …

The effects of solid and liquid lipids on the physicochemical properties of nanostructured lipid carriers

M Apostolou, S Assi, AA Fatokun, I Khan - Journal of pharmaceutical …, 2021 - Elsevier
The aim of this work was to identify from a review of current literature the effects of lipids
used in the development of Nanostructured Lipid Carriers (NLCs) on the physicochemical …

Neuroprotective potential of curcumin-loaded nanostructured lipid carrier in an animal model of Alzheimer's disease: Behavioral and biochemical evidence

S Sadegh Malvajerd, Z Izadi, A Azadi… - Journal of …, 2019 - content.iospress.com
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases and is
caused by accumulation of amyloid-ß (Aß) peptide and is associated with neurological …

Novel bio-inspired lipid nanoparticles for improving the anti-tumoral efficacy of fisetin against breast cancer

SM Talaat, YSR Elnaggar, SO El-Ganainy… - International Journal of …, 2022 - Elsevier
According to the recent Global Cancer Statistics, female breast cancer (BC) is considered
the most commonly diagnosed cancer in 2020 surpassing lung cancer and also, the fifth …

Resveratrol anchored nanostructured lipid carrier loaded in situ gel via nasal route: Formulation, optimization and in vivo characterization

AP Rajput, SB Butani - Journal of drug delivery science and technology, 2019 - Elsevier
The purpose of the present study was to formulate resveratrol loaded nanostructured lipid
carrier based in situ gel for intranasal administration. Resveratrol loaded lipid carrier was …

Impact of liquid lipid on development and stability of trimyristin nanostructured lipid carriers for oral delivery of resveratrol

C Houacine, D Adams, KK Singh - Journal of Molecular Liquids, 2020 - Elsevier
Nanostructured lipid carriers (NLCs) have emerged as versatile carriers to improve oral
bioavailability of poorly water-soluble drugs as well as to protect labile drugs from …

Development, optimization and evaluation of surfactant-based pulmonary nanolipid carrier system of paclitaxel for the management of drug resistance lung cancer …

P Kaur, T Garg, G Rath, RSR Murthy, AK Goyal - Drug delivery, 2016 - Taylor & Francis
In the present study, nanostructured lipid carriers (NLCs) along with various surfactants
loaded with paclitaxel (PTX) were prepared by an emulsification technique using a Box …