Applications of artificial intelligence and machine learning algorithms to crystallization

C Xiouras, F Cameli, GL Quillo… - Chemical …, 2022 - ACS Publications
Artificial intelligence and specifically machine learning applications are nowadays used in a
variety of scientific applications and cutting-edge technologies, where they have a …

A review on the modernization of pharmaceutical development and manufacturing–Trends, perspectives, and the role of mathematical modeling

F Destro, M Barolo - International Journal of Pharmaceutics, 2022 - Elsevier
Recently, the pharmaceutical industry has been facing several challenges associated to the
use of outdated development and manufacturing technologies. The return on investment on …

Assessment of recent process analytical technology (PAT) trends: a multiauthor review

LL Simon, H Pataki, G Marosi, F Meemken… - … Process Research & …, 2015 - ACS Publications
This multiauthor review article aims to bring readers up to date with some of the current
trends in the field of process analytical technology (PAT) by summarizing each aspect of the …

[HTML][HTML] Recent developments in the crystallization process: toward the pharmaceutical industry

Z Gao, S Rohani, J Gong, J Wang - Engineering, 2017 - Elsevier
Crystallization is one of the oldest separation and purification unit operations, and has
recently contributed to significant improvements in producing higher-value products with …

A perspective on Quality-by-Control (QbC) in pharmaceutical continuous manufacturing

Q Su, S Ganesh, M Moreno, Y Bommireddy… - Computers & Chemical …, 2019 - Elsevier
Abstract The Quality-by-Design (QbD) guidance issued by the US Food and Drug
Administration (FDA) has catalyzed the modernization of pharmaceutical manufacturing …

Recent advances in the monitoring, modelling and control of crystallization systems

ZK Nagy, G Fevotte, H Kramer, LL Simon - Chemical Engineering Research …, 2013 - Elsevier
Crystallization is one of the most important unit operations used for the separation and
purification of crystalline solid products. Appropriate design and control of the crystallization …

A study of membrane distillation and crystallization for lithium recovery from high-concentrated aqueous solutions

CA Quist-Jensen, A Ali, S Mondal, F Macedonio… - Journal of Membrane …, 2016 - Elsevier
Membrane distillation is emerging as an interesting solution to address the difficulties and
limits of conventional pressure driven membrane processes to treat highly concentrated …

Introducing hybrid modeling with time-series-transformers: A comparative study of series and parallel approach in batch crystallization

N Sitapure, J Sang-Il Kwon - Industrial & Engineering Chemistry …, 2023 - ACS Publications
Given the hesitance surrounding the direct implementation of black-box tools due to safety
and operational concerns, fully data-driven deep-neural-network (DNN)-based digital twins …

[HTML][HTML] Interfacial ice sprouting during salty water droplet freezing

F Chu, S Li, C Zhao, Y Feng, Y Lin, X Wu, X Yan… - Nature …, 2024 - nature.com
Icing of seawater droplets is capable of causing catastrophic damage to vessels, buildings,
and human life, yet it also holds great potential for enhancing applications such as droplet …

[HTML][HTML] Designs of continuous-flow pharmaceutical crystallizers: developments and practice

M Jiang, RD Braatz - CrystEngComm, 2019 - pubs.rsc.org
Crystallization is an effective, low-cost purification & formulation process widely applied to
pharmaceuticals and fine chemicals. This review describes recent advances in research on …