Repairing the human brain after stroke: I. Mechanisms of spontaneous recovery

SC Cramer - Annals of neurology, 2008 - Wiley Online Library
Stroke remains a leading cause of adult disability. Some degree of spontaneous behavioral
recovery is usually seen in the weeks after stroke onset. Variability in recovery is substantial …

Activation likelihood estimation meta-analysis of motor-related neural activity after stroke

AK Rehme, SB Eickhoff, C Rottschy, GR Fink… - Neuroimage, 2012 - Elsevier
Over the past two decades, several functional neuroimaging experiments demonstrated
changes in neural activity in stroke patients with motor deficits. Conclusions from single …

Brain–computer interface boosts motor imagery practice during stroke recovery

F Pichiorri, G Morone, M Petti, J Toppi… - Annals of …, 2015 - Wiley Online Library
Objective Motor imagery (MI) is assumed to enhance poststroke motor recovery, yet its
benefits are debatable. Brain–computer interfaces (BCIs) can provide instantaneous and …

Repetitive bilateral arm training and motor cortex activation in chronic stroke: a randomized controlled trial

AR Luft, S McCombe-Waller, J Whitall, LW Forrester… - Jama, 2004 - jamanetwork.com
ContextReorganization in central motor networks occurs during early recovery from
hemiparetic stroke. In chronic stroke survivors, specific rehabilitation therapy can improve …

Multimodal imaging of brain reorganization in motor areas of the contralesional hemisphere of well recovered patients after capsular stroke

C Gerloff, K Bushara, A Sailer, EM Wassermann… - Brain, 2006 - academic.oup.com
Clinical recovery after stroke can be significant and has been attributed to plastic
reorganization and recruitment of novel areas previously not engaged in a given task. As …

Hydrogel-delivered brain-derived neurotrophic factor promotes tissue repair and recovery after stroke

DJ Cook, C Nguyen, HN Chun… - Journal of Cerebral …, 2017 - journals.sagepub.com
Stroke is the leading cause of adult disability. Systemic delivery of candidate neural repair
therapies is limited by the blood–brain barrier and off-target effects. We tested a …

Neural function, injury, and stroke subtype predict treatment gains after stroke

E Burke Quinlan, L Dodakian, J See… - Annals of …, 2015 - Wiley Online Library
Objective This study was undertaken to better understand the high variability in response
seen when treating human subjects with restorative therapies poststroke. Preclinical studies …

Applications of fMRI in translational medicine and clinical practice

PM Matthews, GD Honey, ET Bullmore - Nature Reviews Neuroscience, 2006 - nature.com
Functional MRI (fMRI) has had a major impact in cognitive neuroscience. fMRI now has a
small but growing role in clinical neuroimaging, with initial applications to neurosurgical …

Rasch analysis staging methodology to classify upper extremity movement impairment after stroke

ML Woodbury, CA Velozo, LG Richards… - Archives of physical …, 2013 - Elsevier
Abstract Objectives To define Fugl-Meyer Assessment of the Upper Extremity (FMA-UE)
cutoff scores that demarcate 1 level of upper extremity (UE) impairment from another, and …

Arm function after stroke: from physiology to recovery

JW Krakauer - Seminars in neurology, 2005 - thieme-connect.com
There are varying degrees of spontaneous improvement in arm paresis over the first 6
months after stroke. The degree of improvement at 6 months is best predicted by the motor …