As global temperatures continue to rise, extreme heat events are becoming more frequent
and intense. Extreme heat affects cardiovascular health as it is associated with a greater risk …

Irrespective of the reason for hypoperfusion, hypocoagulable and/or hyperfibrinolytic
hemostatic aberrancies afflict up to one-quarter of critically ill patients in shock. Intensivists …

Intermittent fasting and exercise provide neuroprotection from agerelated cognitive decline.
A link between these two seemingly distinct stressors is their capability to steer the brain …

Pharmacological agents used to treat or manage diseases can modify the level of heat strain
experienced by chronically ill and elderly patients via different mechanistic pathways …

Hypo-and hyperthermia affect both primary and secondary hemostasis; however, there are
controversial data concerning platelet activation and the underlying mechanisms under …

Schulte et al. assessed the effect of daily maximum temperature on morbidity and mortality in
9 cardiovascular disease groups across Switzerland. The study was based on medical and …

Background A considerable body of clinical evidence suggests that systemic dehydration
can negatively affect voice production, leading to the common recommendation to rehydrate …

Objectives: The Endocrine and Metabolic Responses on Overtraining Syndrome (EROS)
study identified multiple hormonal and metabolic conditioning processes in athletes, and …

Preserving the hydration status means to balance daily fluids and salt losses with gains,
where the losses depend on several physiological and environmental factors. Especially for …

BACKGROUND Shock index (SI) equals the ratio of heart rate (HR) to systolic blood
pressure (SBP) with clinical evidence that it is more sensitive for trauma patient status …