Snakebite envenoming from a global perspective: Towards an integrated approach

JM Gutiérrez, D Williams, HW Fan, DA Warrell - Toxicon, 2010 - Elsevier
Snakebite envenoming is a neglected public health challenge of compelling importance in
many regions of the world, particularly sub-Saharan Africa, Asia, Latin America and Papua …

Current treatment for venom-induced consumption coagulopathy resulting from snakebite

K Maduwage, GK Isbister - PLoS neglected tropical diseases, 2014 - journals.plos.org
Venomous snakebite is considered the single most important cause of human injury from
venomous animals worldwide. Coagulopathy is one of the commonest important systemic …

Estimate of the burden of snakebites in sub-Saharan Africa: a meta-analytic approach

JP Chippaux - Toxicon, 2011 - Elsevier
Snakebites represent an important neglected public health problem in many developing
countries. There is a lack of epidemiological data, which would be very useful for the …

[图书][B] Handbook of venoms and toxins of reptiles

SP Mackessy - 2016 - taylorfrancis.com
The Handbook of Venoms and Toxins of Reptiles offers" one-stop shopping" to all biologists,
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …

Ending the drought: new strategies for improving the flow of affordable, effective antivenoms in Asia and Africa

DJ Williams, JM Gutiérrez, JJ Calvete, W Wüster… - Journal of …, 2011 - Elsevier
The development of snake antivenoms more than a century ago should have heralded
effective treatment of the scourge of snakebite envenoming in impoverished, mostly rural …

Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms

G León, M Herrera, Á Segura, M Villalta, M Vargas… - Toxicon, 2013 - Elsevier
Snake antivenoms are formulations of immunoglobulins, or immunoglobulin fragments,
purified from the plasma of animals immunized with snake venoms. Their therapeutic …

Antivenoms for the treatment of snakebite envenomings: the road ahead

JM Gutiérrez, G León, T Burnouf - Biologicals, 2011 - Elsevier
The parenteral administration of antivenoms is the cornerstone of snakebite envenoming
therapy. Efforts are made to ensure that antivenoms of adequate efficacy and safety are …

Snake antivenoms: antivenoms

DG Lalloo*, RDG Theakston - Journal of Toxicology: Clinical …, 2003 - Taylor & Francis
The concept of antivenoms was first developed by Henry Sewall in 1887 when he
demonstrated that pigeons could be immunized against the effects of pygmy rattlesnake …

[图书][B] Snakes of central and western Africa

JP Chippaux, K Jackson - 2019 - books.google.com
The first—and only—authoritative guide to the snakes of Central and Western Africa.
Nobody knows exactly how many snake species live in the biodiversity hotspots of Western …

Antivenoms for snakebite envenomings

J Maria Gutierrez, G León, B Lomonte… - Inflammation & Allergy …, 2011 - ingentaconnect.com
Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming.
Antivenoms are manufactured by immunizing animals, usually horses, with venoms from a …