The Landscape of Monogenic Parkinson's Disease in Populations of Non-European Ancestry: A Narrative Review
C Koros, A Bougea, AM Simitsi, N Papagiannakis… - Genes, 2023 - mdpi.com
Introduction: There has been a bias in the existing literature on Parkinson's disease (PD)
genetics as most studies involved patients of European ancestry, mostly in Europe and …
genetics as most studies involved patients of European ancestry, mostly in Europe and …
Advancing precision medicine therapeutics for Parkinson's utilizing a shared quantitative systems pharmacology model and framework
C Denaro, D Stephenson, MLTM Müller… - Frontiers in Systems …, 2024 - frontiersin.org
A rich pipeline of therapeutic candidates is advancing for Parkinson's disease, many of
which are targeting the underlying pathophysiology of disease. Emerging evidence …
which are targeting the underlying pathophysiology of disease. Emerging evidence …
Global Perspectives on Returning Genetic Research Results in Parkinson's Disease
In the era of precision medicine, genetic test results have become increasingly relevant in
the care of patients with Parkinson's disease (PD) and their families. While large PD …
the care of patients with Parkinson's disease (PD) and their families. While large PD …
[HTML][HTML] Understanding monogenic Parkinson's disease at a global scale
J Junker, LM Lange, EJ Vollstedt, K Roopnarain… - medRxiv, 2024 - ncbi.nlm.nih.gov
Until recently, about three-quarters of all monogenic Parkinson's disease (PD) studies were
performed in European/White ancestry, thereby severely limiting our insights into genotype …
performed in European/White ancestry, thereby severely limiting our insights into genotype …
Genome-wide analysis identifies non-reference transposable element polymorphisms associated with Parkinson's disease
H Wu, J Luo, G Liu - Global Translational Medicine, 2023 - accscience.com
Parkinson's disease (PD) is a common neurodegenerative disease that primarily affects the
elderly, significantly impacting patients' health and quality of life. While most genetic studies …
elderly, significantly impacting patients' health and quality of life. While most genetic studies …
[HTML][HTML] Advancing PD care with a global focus
N Okubadejo, O Ojo - movementdisorders.org
The session kicked off with Shen's lecture “Uncovering the genetic basis of Parkinson's
disease worldwide.” He started his talk by showing clinical vignettes of multiethnic …
disease worldwide.” He started his talk by showing clinical vignettes of multiethnic …