Circular RNAs (circRNAs) are closed long non-coding RNAs, in which the 5'and 3'termini
are covalently linked by back-splicing of exons from a single pre-mRNA. Emerging evidence …

Abstract In May 2014, the National Institutes of Health (NIH) stated its intent to “require
applicants to consider sex as a biological variable (SABV) in the design and analysis of NIH …

© 2015 Macmillan Publishers Limited. All rights reserved ducts, one of which can form the
uterus and Fallopian tubes, and the other the male internal genital plumbing: the …

Studies have shown differences in specific cognitive ability domains and risk of Alzheimer's
disease between the men and women at later age. However it is important to know that sex …

Sexual reproduction is a fundamental aspect of life. It is defined by the occurrence of meiosis
and the fusion of two gametes of different sexes or mating types. Sex-determination …

The initiation of male development in mammals requires one or more genes on the Y
chromosome. A recently isolated gene, termed SRY in humans and Sry in mouse, has many …

SOX4 is an essential developmental transcription factor that regulates stemness,
differentiation, progenitor development, and multiple developmental pathways including …

The spinal cord receives input from peripheral sensory neurons and controls motor output by
regulating muscle innervating motor neurons. These functions are carried out by neural …

Human genomes are 99.9 percent identical—with one prominent exception. Instead of a
matching pair of X chromosomes, men carry a single X, coupled with a tiny chromosome …

A human autosomal XY sex reversal locus, SRA1, associated with the skeletal malformation
syndrome campomelic dysplasia (CMPD1), has been placed at distal 17q. The SOX9 gene …