An overview on the recent advances in alternative solvents as stabilizers of proteins and enzymes
JS Almeida, EV Capela, AM Loureiro, APM Tavares… - ChemEngineering, 2022 - mdpi.com
Currently, the use of alternative solvents is increasing, namely ionic liquids (ILs) and deep
eutectic solvents (DESs) in diverse fields of knowledge, such as biochemistry, chemistry …
eutectic solvents (DESs) in diverse fields of knowledge, such as biochemistry, chemistry …
Hydration in deep eutectic solvents induces non-monotonic changes in the conformation and stability of proteins
A Sanchez-Fernandez, M Basic, J Xiang… - Journal of the …, 2022 - ACS Publications
The preservation of labile biomolecules presents a major challenge in chemistry, and deep
eutectic solvents (DESs) have emerged as suitable environments for this purpose. However …
eutectic solvents (DESs) have emerged as suitable environments for this purpose. However …
Investigating biomolecules in deep eutectic solvents with molecular dynamics simulations: current state, challenges and future perspectives
JP Bittner, I Smirnova, S Jakobtorweihen - Molecules, 2024 - mdpi.com
Deep eutectic solvents (DESs) have recently gained increased attention for their potential in
biotechnological applications. DESs are binary mixtures often consisting of a hydrogen bond …
biotechnological applications. DESs are binary mixtures often consisting of a hydrogen bond …
Comprehending the intermolecular interaction of JAK inhibitor fedratinib with bovine serum albumin (BSA)/human alpha-1-acid glycoprotein (HAG): Multispectral …
SL Jiang, WJ Wang, ZY Hu, RJ Zhang, JH Shi - Spectrochimica Acta Part A …, 2024 - Elsevier
The primary coverage of this paper is to investigate the molecular interaction of JAK2
inhibitor, fedratinib (FED) with BSA/HAG proteins through multispectral approaches and …
inhibitor, fedratinib (FED) with BSA/HAG proteins through multispectral approaches and …
Unveiling the influence of hydrated deep eutectic solvents on the dynamics of water–soluble proteins
Deep eutectic solvents (DESs) are mixtures of two or more pure compounds (eg, Lewis or
Brønsted acids and bases, anionic and/or cationic species) in a well-defined stoichiometric …
Brønsted acids and bases, anionic and/or cationic species) in a well-defined stoichiometric …
Stabilization of Non-Native Folds and Programmable Protein Gelation in Compositionally Designed Deep Eutectic Solvents
A Sanchez-Fernandez, JF Poon, AE Leung… - ACS …, 2024 - ACS Publications
Proteins are adjustable units from which biomaterials with designed properties can be
developed. However, non-native folded states with controlled topologies are hardly …
developed. However, non-native folded states with controlled topologies are hardly …
An innovative, low-cost and environment-friendly approach by using a deep eutectic solvent as the water substitute to minimize waste in the textile industry and for …
With the increase in environmental protection awareness, the development of strategies to
reduce effluent and lower the cost of the chemical reagents used in the textile wetting …
reduce effluent and lower the cost of the chemical reagents used in the textile wetting …
Origin of structural and dynamic heterogeneity in thymol and coumarin-based hydrophobic deep eutectic solvents as revealed by molecular dynamics
A Malik, HK Kashyap - Physical Chemistry Chemical Physics, 2023 - pubs.rsc.org
Hydrophobic deep eutectic solvents (HDESs) have recently emerged as a class of water-
immiscible solvents with greener starting materials and inherent hydrophobic character …
immiscible solvents with greener starting materials and inherent hydrophobic character …
Assessing the impact of choline chloride and benzyltrimethylammonium chloride-based deep eutectic solvents on the structure and conformational dynamics of bovine …
S Barik, A Mahapatra, N Preeyanka… - Physical Chemistry …, 2023 - pubs.rsc.org
Although deep eutectic solvents (DESs) are regarded as useful substitutes for both ionic
liquids and common organic solvents for storage and applications of biomolecules, it is still …
liquids and common organic solvents for storage and applications of biomolecules, it is still …
Protein stability in a natural deep eutectic solvent: Preferential hydration or solvent slaving?
Deep eutectic solvents (DESs) emerged as potential alternative solvent media in multiple
areas, including biomolecular (cryo) preservation. Herein, we studied the stability of a small …
areas, including biomolecular (cryo) preservation. Herein, we studied the stability of a small …