Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …

Melatonin is uncommonly effective in reducing oxidative stress under a remarkably large
number of circumstances. It achieves this action via a variety of means: direct detoxification …

Aging and various age-related diseases are associated with reductions in melatonin
secretion, proinflammatory changes in the immune system, a deteriorating circadian system …

Prevention of neurodegenerative diseases is presently a major goal for our Society and
melatonin, an unusual phylogenetically conserved molecule present in all aerobic …

Alzheimer's Disease (AD) is a neurodegenerative disorder related with the increase of age
and it is the main cause of dementia in the world. AD affects cognitive functions, such as …

Alzheimer's disease (AD) is a chronic, progressive and prevalent neurodegenerative
disease characterized by the loss of higher cognitive functions and an associated loss of …

Melatonin is an ancient molecule that is evident in high concentrations in various tissues
throughout the body. It can be separated into two pools; one of which is synthesized by the …

As a member of the A Disintegrin And Metalloproteinase (ADAM) family, ADAM10 has been
identified as the constitutive α-secretase in the process of amyloid-β protein precursor …

Neurodegenerative diseases are caused by the gradual loss of neurons' function. These
neurological illnesses remain incurable, and current medicines only alleviate the symptoms …

ADAM10 (A Disintegrin and Metalloproteinase 10) has been identified as the major
physiological alpha-secretase in neurons, responsible for cleaving APP in a non …