The word “limonoids” originated from the bitterness of lemon or other citrus fruit. Structurally,
limonoids are formed by loss of four terminal carbons of the side chain in the apotirucallane …

Swietenia is a genus in the plant family Meliaceae. This genus contains seven to eight
known species, found in the tropical and subtropical regions of the Americas and West …

Eighteen new tetranortriterpenoids were isolated from the cotyledons of Swietenia
mahagoni (Meliaceac) along with ten known tetranortriterpenoids. Among them, the …

Eight new tetranortriterpenoids, swietemahonin A—G and swietemahonolide, were isolated
from the cotyledons of seeds of Swietenia mahagom '. The structures 1—8 are proposed for …

Eleven new mexicanolide-type limonoids, swietmanins A− I (1− 4, 7− 11), 2-hydroxy-3-O-
isobutyrylproceranolide (5), 2-hydroxy-3-O-benzoylproceranolide (6), and a new andirobin …

Sixteen new D-ring-opened phragmalin limonoid orthoesters, swietenitins A− M (1− 6, 8, 10,
12− 16), 2-acetoxyswietenialide D (7), 2, 11-diacetoxyswietenialide D (9), and 11 …

A PAF antagonist, chatancin, was isolated from a soft coral, Sarcophyton sp. Its structure (la)
was de-termined to be (lP, 2S, 4a)?, 4bf?, 7S, 8aS, 10af?)-4a, 7-di-methyl-l, 8a-epoxy-l …

Publisher Summary This chapter discusses the chemistry, pharmacology, and clinical
applications of the antagonists of platelet-activating factor (PAF). The existence of specific …

The modified limonoids isolated from the Meliaceae are too complex or obtained in too small
quantities to determine their structures by chemical and spectroscopic means, including 1H …

A compilation of over 700 secondary plant metabolites known to exhibit cardiovascular
activity is presented. For each metabolite, a plant source, type of activity, the structural class …