Epilepsies are chronic neurological diseases that affect approximately 2% of the world
population. In addition to being one of the most frequent neurological disorders, treatment …

The hippocampus exhibits a wide range of epilepsy-related abnormalities and is situated in
the mesial temporal lobe, where limbic seizures begin. These abnormalities could affect …

Mesial temporal lobe epilepsy (MTLE) is usually associated with drug-resistant seizures and
cognitive deficits. Efforts have been made to improve the understanding of the …

Granule cell dispersion (GCD) is a common pathological feature observed in the
hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms …

Abstract Information about epileptogenesis-associated changes in protein expression
patterns is of particular interest for future selection of target and biomarker candidates …

O artigo apresenta uma breve revisão sobre os achados históricos, epidemiológicos,
tratamento e perspectivas terapêuticas para as epilepsias, com enfoque na epilepsia do …

Over 50 million people worldwide are affected by epilepsy, a common neurological disorder
that has a high rate of drug resistance and diverse comorbidities such as progressive …

Proteomics has helped us to understand physiological functioning as well as pathological
condition. Mesial temporal lobe epilepsy (MTLE), the most common type of focal epilepsy in …

Epilepsy has many causes and comorbidities affecting as many as 4% of people in their
lifetime. Both idiopathic and symptomatic epilepsies are highly heritable, but genetic factors …

In adult rats, the administration of lithium–pilocarpine (LiPilo) reproduces most clinical and
neuropathological features of human temporal lobe epilepsy (TLE). Carisbamate (CRS) …