Comparison of different probes based on labeled annexin V for detection of apoptosis

M Nazari, A Minai-Tehrani, R Emamzadeh - RSC advances, 2014 - pubs.rsc.org
Apoptosis is a well-organized mechanism developed by eukaryotic organisms during
maturation. The importance of apoptosis as a major form of cellular suicide with a causative …

Fast and highly efficient purification of 6× histidine-tagged recombinant proteins by Ni-decorated MnFe 2 O 4@ SiO 2@ NH 2@ 2AB as novel and efficient affinity …

Z Rashid, H Naeimi, AH Zarnani, M Nazari… - RSC …, 2016 - pubs.rsc.org
The present study is aimed at the synthesis of MnFe2O4@ SiO2@ NH2@ 2AB-Ni, as a
highly efficient and novel affinity adsorbent, for specific purification of 6× histidine-tagged …

Super RLuc8: a novel engineered Renilla luciferase with a red-shifted spectrum and stable light emission

S Rahnama, B Saffar, ZF Kahrani, M Nazari… - Enzyme and microbial …, 2017 - Elsevier
Renilla luciferase is a bioluminescent enzyme which is broadly used as a reporter protein in
molecular biosensors. In this study, a novel luciferase with desired light emission …

An enhanced bioluminescence-based Annexin V probe for apoptosis detection in vitro and in vivo

T Head, P Dau, S Duffort, P Daftarian, PM Joshi… - Cell death & …, 2017 - nature.com
The process of controlled cellular death known as apoptosis has an important central role
not only in normal homeostatic maintenance of tissues, but also in numerous diseases such …

Development of a bioluminescent homogenous nanobody-based immunoassay for the detection of prostate-specific antigen (PSA)

ME Baghdadi, R Emamzadeh, M Nazari… - Enzyme and Microbial …, 2024 - Elsevier
Prostate cancer is the most prevalent cancer in men. At present, the diagnosis and
screening of prostate cancer rely on the essential biomarker known as prostate-specific …

FcUni-RLuc: an engineered Renilla luciferase with Fc binding ability and light emission activity

A Farzannia, R Roghanian, SH Zarkesh-Esfahani… - Analyst, 2015 - pubs.rsc.org
A novel and advanced Fc-binding probe–FcUni-RLuc namely–has been produced and
functionally assayed for labelling IgGs. The Fc antibody binding sequence–HWRGWV–was …

Molecular basis of thermostability enhancement of Renilla luciferase at higher temperatures by insertion of a disulfide bridge into the structure

ZF Kahrani, R Emamzadeh, M Nazari… - Biochimica et Biophysica …, 2017 - Elsevier
Renilla luciferase (RLuc), also known as Renilla-luciferin 2-monooxygenase, is a light
producing enzyme used in many biotechnological applications such as bioreporters …

Structural studies and cell proliferation activity of human Follistatin-like 1 in reducing and non-reducing conditions

SS Jafari, R Emamzadeh, M Nazari… - Process …, 2023 - Elsevier
Human Follistatin-like 1, is a protein with multiple disulfide bonds involved in important
physiological processes. The current research aimed to evaluate the relationship between …

Development of recombinant biomimetic nano-carrier for targeted gene transfer to HER3 positive breast cancer

M Nazari, A Minai-Tehrani, S Mousavi… - International Journal of …, 2021 - Elsevier
Human epidermal growth factor receptor 3 (HER3) has rapidly gained much attention as a
promising target for cancer treatment. The increasing recognition of HER3 roles in a number …

A luminescent biosensor for ex vivo detection of HER2-positive breast cancer based on a novel affiprobe

M Nazari, R Emamzadeh, A Minai-Tehrani… - Analytical …, 2019 - pubs.rsc.org
A novel receptor tyrosine-protein kinase erbB-2 (HER2)-binding affiprobe–named ZHER2:
342-RLuc–was designed, produced and assessed in terms of function to detect HER2 …