RNA modifications: importance in immune cell biology and related diseases
L Cui, R Ma, J Cai, C Guo, Z Chen, L Yao… - Signal transduction and …, 2022 - nature.com
RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …
including generation, transportation, function, and metabolization, they act as critical …
How RNA modifications regulate the antiviral response
Induction of the antiviral innate immune response is highly regulated at the RNA level,
particularly by RNA modifications. Recent discoveries have revealed how RNA …
particularly by RNA modifications. Recent discoveries have revealed how RNA …
Spike Protein NTD mutation G142D in SARS-CoV-2 Delta VOC lineages is associated with frequent back mutations, increased viral loads, and immune evasion
The significantly greater infectivity of the SARS-CoV-2 Delta variants of concern (VOC) is
hypothesized to be driven by key mutations that result in increased transmissibility, viral load …
hypothesized to be driven by key mutations that result in increased transmissibility, viral load …
The mutational landscape of SARS-CoV-2
B Saldivar-Espinoza, P Garcia-Segura… - International Journal of …, 2023 - mdpi.com
Mutation research is crucial for detecting and treating SARS-CoV-2 and developing
vaccines. Using over 5,300,000 sequences from SARS-CoV-2 genomes and custom Python …
vaccines. Using over 5,300,000 sequences from SARS-CoV-2 genomes and custom Python …
Host-mediated RNA editing in viruses
Viruses rely on hosts for life and reproduction, cause a variety of symptoms from common
cold to AIDS to COVID-19 and provoke public health threats claiming millions of lives around …
cold to AIDS to COVID-19 and provoke public health threats claiming millions of lives around …
Prediction of recurrent mutations in SARS-CoV-2 using artificial neural networks
B Saldivar-Espinoza, G Macip… - International Journal of …, 2022 - mdpi.com
Predicting SARS-CoV-2 mutations is difficult, but predicting recurrent mutations driven by the
host, such as those caused by host deaminases, is feasible. We used machine learning to …
host, such as those caused by host deaminases, is feasible. We used machine learning to …
Inosine and its methyl derivatives: Occurrence, biogenesis, and function in RNA
Inosine is one of the most common post-transcriptional modifications. Since its discovery, it
has been noted for its ability to contribute to non-Watson-Crick interactions within RNA …
has been noted for its ability to contribute to non-Watson-Crick interactions within RNA …
The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections
Emerging evidence highlights the multifaceted roles of the RNA epitranscriptome during
viral infections. By modulating the modification landscape of viral and host RNAs, viruses …
viral infections. By modulating the modification landscape of viral and host RNAs, viruses …
Potential mechanisms for human genome integration of genetic code from SARS-CoV-2 mRNA vaccination
AM Kyriakopoulos, PA Mccullough, G Nigh… - Authorea …, 2022 - advance.sagepub.com
Background The findings of a sequence embedded in Human DNA that was almost identical
to a sequence in the SARS-CoV-2 genome, and the identification of plausible integration of …
to a sequence in the SARS-CoV-2 genome, and the identification of plausible integration of …
The regulation of antiviral innate immunity through non-m6A RNA modifications
The post-transcriptional RNA modifications impact the dynamic regulation of gene
expression in diverse biological and physiological processes. Host RNA modifications play …
expression in diverse biological and physiological processes. Host RNA modifications play …