Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases,
characterized by impaired cognitive function due to progressive loss of neurons in the brain …

Neuroinflammation is a central mechanism involved in neurodegeneration as observed in
Alzheimer's disease (AD), the most prevalent form of neurodegenerative disease …

Technologies for imaging the pathophysiology of Alzheimer disease (AD) now permit
studies of the relationships between the two major proteins deposited in this disease …

UK Biobank is a large-scale prospective epidemiological study with all data accessible to
researchers worldwide. It is currently in the process of bringing back 100,000 of the original …

Medical imaging has enormous potential for early disease prediction, but is impeded by the
difficulty and expense of acquiring data sets before symptom onset. UK Biobank aims to …

Understanding the amazingly complex human cerebral cortex requires a map (or
parcellation) of its major subdivisions, known as cortical areas. Making an accurate areal …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder leading to loss of
cognitive abilities and ultimately, death. With no cure available, limited treatments mostly …

The function of neural circuits and networks can be controlled, in part, by modulating the
synchrony of their components' activities. Network hypersynchrony and altered oscillatory …

Resting-state functional magnetic resonance imaging (rs-fMRI) offers the opportunity to
delineate individual-specific brain networks. A major question is whether individual-specific …

We present a practical “how-to” guide to help determine whether single-subject fMRI
independent components (ICs) characterise structured noise or not. Manual identification of …