An overview of the modulatory effects of oleic acid in health and disease

H Sales-Campos, P Reis de Souza… - Mini reviews in …, 2013 - ingentaconnect.com
Evidences in the last years have showed the effects of oleic acid (OA) in human health and
disease. Olive oil, rich in oleic acid, is supposed to present modulatory effects in a wide …

Glycerolipid metabolism and signaling in health and disease

M Prentki, SRM Madiraju - Endocrine reviews, 2008 - academic.oup.com
Maintenance of body temperature is achieved partly by modulating lipolysis by a network of
complex regulatory mechanisms. Lipolysis is an integral part of the glycerolipid/free fatty …

Acute respiratory distress syndrome: role of oleic acid‐triggered lung injury and inflammation

CF Gonçalves-de-Albuquerque, AR Silva… - Mediators of …, 2015 - Wiley Online Library
Lung injury especially acute respiratory distress syndrome (ARDS) can be triggered by
diverse stimuli, including fatty acids and microbes. ARDS affects thousands of people …

Curcumin-loaded ultradeformable nanovesicles as a potential delivery system for breast cancer therapy

SM Abdel-Hafez, RM Hathout, OA Sammour - Colloids and Surfaces B …, 2018 - Elsevier
In the current study, the transdermal route has been investigated to deliver the poorly
bioavailable drug; curcumin into the systemic circulation, aiming to target both superficial …

Formulative study and intracellular fate evaluation of ethosomes and transethosomes for vitamin D3 delivery

M Costanzo, E Esposito, M Sguizzato… - International journal of …, 2021 - mdpi.com
In this pilot study, ethosomes and transethosomes were investigated as potential delivery
systems for cholecalciferol (vitamin D3), whose deficiency has been correlated to many …

Adipocyte fatty acid-binding protein promotes palmitate-induced mitochondrial dysfunction and apoptosis in macrophages

H Li, Y Xiao, L Tang, F Zhong, G Huang, JM Xu… - Frontiers in …, 2018 - frontiersin.org
A high level of circulating free fatty acids (FFAs) is known to be an important trigger for
macrophage apoptosis during the development of atherosclerosis. However, the underlying …

Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in rabbit

A Leonardi, C Bucolo, F Drago, S Salomone… - International journal of …, 2015 - Elsevier
The study was aimed at evaluating whether the ocular hypotensive effect of melatonin (MEL)
was enhanced by its encapsulation in cationic solid lipid nanoparticles (cSLN), as well as at …

Lauric acid, a dietary saturated medium-chain fatty acid, elicits calcium-dependent eryptosis

MA Alfhili, GS Aljuraiban - Cells, 2021 - mdpi.com
Cardiovascular diseases (CVD) are a leading cause of mortality worldwide, and dietary
habits represent a major risk factor for dyslipidemia; a hallmark of CVD. Saturated fatty acids …

The biological activities of protein/oleic acid complexes reside in the fatty acid

A Fontana, B Spolaore, PP de Laureto - Biochimica et Biophysica Acta …, 2013 - Elsevier
A complex formed by human α-lactalbumin (α-LA) and oleic acid (OA), named HAMLET, has
been shown to have an apoptotic activity leading to the selective death of tumor cells. In …

Cytotoxicity of submicron emulsions and solid lipid nanoparticles for dermal application

W Weyenberg, P Filev, D Van den Plas… - International journal of …, 2007 - Elsevier
The cytotoxicity and physical properties of various submicron O/W emulsions and solid lipid
nanoparticles for dermal applications were investigated. Droplet size and zetapotential of …