NO donors as the wonder molecules with therapeutic potential: Recent trends and future perspectives
Nitric oxide (NO), an endogenous, free radical, highly unstable, diatomic gaseous molecule,
plays crucial roles in several physiological and pathological processes. It has attracted …
plays crucial roles in several physiological and pathological processes. It has attracted …
Recent advances in the chemistry of iron-based chemotherapeutic agents
The discovery of cisplatin followed by its success in anticancer therapy laid the foundation of
metal-based drug design and development. Further research led to discovery of other …
metal-based drug design and development. Further research led to discovery of other …
Fe in biosynthesis, translocation, and signal transduction of NO: toward bioinorganic engineering of dinitrosyl iron complexes into NO-delivery scaffolds for tissue …
Iron, the most abundant transition metal ion in humans, participates in the biosynthesis,
translocation, signal transduction, and transformation of nitric oxide through its …
translocation, signal transduction, and transformation of nitric oxide through its …
Cationic dinitrosyl iron complexes with thiourea exhibit selective toxicity to brain tumor cells in vitro
NA Sanina, IV Sulimenkov, NS Emel'yanova… - Dalton …, 2022 - pubs.rsc.org
The cytotoxic activity of a series of dinitrosyl iron complexes (DNICs) with thioureas against
cells of different origin has been studied in this work. The cytotoxicity of the studied DNICs …
cells of different origin has been studied in this work. The cytotoxicity of the studied DNICs …
Effect of solvents and glutathione on the decomposition of the nitrosyl iron complex with N-ethylthiourea ligands: An experimental and theoretical study
ОV Pokidova, NS Emel'yanova, BL Psikha… - Journal of Inorganic …, 2022 - Elsevier
Dinitrosyl iron complexes (DNICs) are a depot and potential source of free NO in organisms.
Their synthetic analog, N-ethylthiourea DNIC [Fe (SC (NH 2)(NHC 2 H 5)) 2 (NO) 2]+ Cl−∙[Fe …
Their synthetic analog, N-ethylthiourea DNIC [Fe (SC (NH 2)(NHC 2 H 5)) 2 (NO) 2]+ Cl−∙[Fe …
Effect of albumin on the transformation of dinitrosyl iron complexes with thiourea ligands
ОV Pokidova, VB Luzhkov, NS Emel'yanova… - Dalton …, 2020 - pubs.rsc.org
Interaction and transformation of the mononuclear cationic dinitrosyl iron complex [Fe (SC
(NH2) 2) 2 (NO) 2]+(complex 1) upon binding with bovine serum albumin (BSA) have been …
(NH2) 2) 2 (NO) 2]+(complex 1) upon binding with bovine serum albumin (BSA) have been …
Insight into the Electronic Structure of Biomimetic Dinitrosyliron Complexes (DNICs): Toward the Syntheses of Amido-Bridging Dinuclear DNICs
CY Tung, YT Tseng, TT Lu, WF Liaw - Inorganic Chemistry, 2021 - ACS Publications
The ubiquitous function of nitric oxide (NO) guided the biological discovery of the natural
dinitrosyliron unit (DNIU)[Fe (NO) 2] as an intermediate/end product after Fe nitrosylation of …
dinitrosyliron unit (DNIU)[Fe (NO) 2] as an intermediate/end product after Fe nitrosylation of …
Investigation of the interaction of the cationic nitrosyl iron complex [Fe (SC (NH2) 2) 2 (NO) 2]+ with molecular oxygen
NS Emel'yanova, LG Gutsev, OV Pokidova… - Inorganica Chimica …, 2021 - Elsevier
The interaction of a nitrosyl iron complex with molecular oxygen was studied with Density
Functional Theory. On the basis our analysis of the geometric and electronic structure of the …
Functional Theory. On the basis our analysis of the geometric and electronic structure of the …
Features of the decomposition of the nitrosyl iron complex with thiourea ligands under aerobic conditions: experiment and kinetic and quantum chemical modeling
OV Pokidova, BL Psikha, NS Emel'yanova… - Russian Chemical …, 2022 - Springer
The reaction of oxygen with the nitrosyl iron complex [Fe (SC (NH2) 2) 2 (NO) 2]+(complex
1) was studied. According to the results obtained, three main directions of transformation of …
1) was studied. According to the results obtained, three main directions of transformation of …
Features of the decomposition of cationic nitrosyl iron complexes with N-ethylthiourea and penicillamine ligands in the presence of albumin
OV Pokidova, AY Kormukhina, AI Kotelnikov… - Inorganica Chimica …, 2021 - Elsevier
In this work, transformations of two cationic dinitrosyl iron complexes (DNICs), namely,
mononuclear with N-ethylthiourea ligands [Fe (SC (NH 2)(NHC 2 H 5)) 2 (NO) 2]+ Cl−∙[Fe …
mononuclear with N-ethylthiourea ligands [Fe (SC (NH 2)(NHC 2 H 5)) 2 (NO) 2]+ Cl−∙[Fe …