Oxidative stress and inflammation in acute and chronic lung injuries

FS Bezerra, M Lanzetti, RT Nesi, AC Nagato, CP Silva… - Antioxidants, 2023 - mdpi.com
Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung
injury can affect several components of the respiratory system, including the airways …

Endocrine disrupting chemicals and disease susceptibility

TT Schug, A Janesick, B Blumberg… - The Journal of steroid …, 2011 - Elsevier
Environmental chemicals have significant impacts on biological systems. Chemical
exposures during early stages of development can disrupt normal patterns of development …

The microbiome: stress, health and disease

RD Moloney, L Desbonnet, G Clarke, TG Dinan… - Mammalian …, 2014 - Springer
Bacterial colonisation of the gut plays a major role in postnatal development and maturation
of key systems that have the capacity to influence central nervous system (CNS) …

The second wave of synthetic biology: from modules to systems

PEM Purnick, R Weiss - Nature reviews Molecular cell biology, 2009 - nature.com
Synthetic biology is a research field that combines the investigative nature of biology with
the constructive nature of engineering. Efforts in synthetic biology have largely focused on …

Environmental chemical exposures and human epigenetics

L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

Developmental programming, a pathway to disease

V Padmanabhan, RC Cardoso… - Endocrinology, 2016 - academic.oup.com
Accumulating evidence suggests that insults occurring during the perinatal period alter the
developmental trajectory of the fetus/offspring leading to long-term detrimental outcomes …

[HTML][HTML] Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing

DA Crain, SJ Janssen, TM Edwards, J Heindel, S Ho… - Fertility and sterility, 2008 - Elsevier
OBJECTIVE: To evaluate the possible role of endocrine-disrupting compounds (EDCs) on
female reproductive disorders emphasizing developmental plasticity and the complexity of …

Environmental epigenetics and its implication on disease risk and health outcomes

SM Ho, A Johnson, P Tarapore, V Janakiram… - ILAR …, 2012 - academic.oup.com
This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …

Relation of DNA Methylation of 5′-CpG Island of ACSL3 to Transplacental Exposure to Airborne Polycyclic Aromatic Hydrocarbons and Childhood Asthma

F Perera, W Tang, J Herbstman, D Tang, L Levin… - PloS one, 2009 - journals.plos.org
In a longitudinal cohort of∼ 700 children in New York City, the prevalence of asthma (>
25%) is among the highest in the US. This high risk may in part be caused by transplacental …

Effects of arsenic exposure on DNA methylation and epigenetic gene regulation

JF Reichard, A Puga - Epigenomics, 2010 - Taylor & Francis
Arsenic is a nonmutagenic human carcinogen that induces tumors through unknown
mechanisms. A growing body of evidence suggests that its carcinogenicity results from …