Vitamin D deficiency: effects on oxidative stress, epigenetics, gene regulation, and aging

SJ Wimalawansa - Biology, 2019 - mdpi.com
Recent advances in vitamin D research indicate that this vitamin, a secosteroid hormone,
has beneficial effects on several body systems other than the musculoskeletal system. Both …

[HTML][HTML] Quitting smoking at or around diagnosis improves the overall survival of lung cancer patients: a systematic review and meta-analysis

S Caini, M Del Riccio, V Vettori, V Scotti… - Journal of Thoracic …, 2022 - Elsevier
Introduction Lung cancer (LC) remains a disease with poor prognosis despite recent
advances in treatments. Here, we aimed at summarizing the current scientific evidence on …

Phase II, Open-Label Study of Encorafenib Plus Binimetinib in Patients With BRAFV600-Mutant Metastatic Non–Small-Cell Lung Cancer

GJ Riely, EF Smit, MJ Ahn, E Felip… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE The combination of encorafenib (BRAF inhibitor) plus binimetinib (MEK inhibitor)
has demonstrated clinical efficacy with an acceptable safety profile in patients with BRAF …

[HTML][HTML] Tobacco smoking after diagnosis of cancer: clinical aspects

J Jassem - Translational lung cancer research, 2019 - ncbi.nlm.nih.gov
Tobacco smoking accounts for at least 30% of all cancer deaths and nearly 90% of lung
cancer deaths. Smoking cessation significantly reduces the risk of developing tobacco …

Association between duration of smoking abstinence before non-small-cell lung cancer diagnosis and survival: a retrospective, pooled analysis of cohort studies

AF Fares, Y Li, M Jiang, MC Brown, ACL Lam… - The Lancet Public …, 2023 - thelancet.com
Background The association between duration of smoking abstinence before non-small-cell
lung cancer (NSCLC) diagnosis and subsequent survival can influence public health …

Impacts of environmental factors on head and neck cancer pathogenesis and progression

M Miranda-Galvis, R Loveless, LP Kowalski, Y Teng - Cells, 2021 - mdpi.com
Epidemiological and clinical studies over the past two decades have provided strong
evidence that genetic elements interacting with environmental components can individually …

Smoking cessation, version 1.2016, NCCN clinical practice guidelines in oncology

PG Shields, RS Herbst, D Arenberg… - Journal of the National …, 2016 - jnccn.org
Cigarette smoking has been implicated in causing many cancers and cancer deaths. There
is mounting evidence indicating that smoking negatively impacts cancer treatment efficacy …

[HTML][HTML] Tobacco smoking and cessation and PD-L1 inhibitors in non-small cell lung cancer (NSCLC): a review of the literature

J Norum, C Nieder - ESMO open, 2018 - Elsevier
Background Programmed death ligand 1 (PD-L1) targeting immunotherapies, as
pembrolizumab and nivolumab, have significantly improved outcome in patients with non …

Smoking cessation after cancer diagnosis and enhanced therapy response: mechanisms and significance

S Chellappan - Current Oncology, 2022 - mdpi.com
The adverse effects of smoking on human health have been recognized for several
decades, especially in the context of cancer. The ability of tobacco smoke components …

The case for prehabilitation prior to breast cancer treatment

D Santa Mina, P Brahmbhatt, C Lopez, J Baima… - PM&R, 2017 - Elsevier
Cancer rehabilitation in breast cancer survivors is well established, and there are many
studies that focus on interventions to treat impairments as well as therapeutic exercise …