Deep learning in ophthalmology: the technical and clinical considerations
The advent of computer graphic processing units, improvement in mathematical models and
availability of big data has allowed artificial intelligence (AI) using machine learning (ML) …
availability of big data has allowed artificial intelligence (AI) using machine learning (ML) …
[HTML][HTML] Doppler optical coherence tomography
Abstract Optical Coherence Tomography (OCT) has revolutionized ophthalmology. Since its
introduction in the early 1990s it has continuously improved in terms of speed, resolution …
introduction in the early 1990s it has continuously improved in terms of speed, resolution …
Discovery and clinical translation of novel glaucoma biomarkers
Glaucoma and other optic neuropathies are characterized by progressive dysfunction and
loss of retinal ganglion cells and their axons. Given the high prevalence of glaucoma-related …
loss of retinal ganglion cells and their axons. Given the high prevalence of glaucoma-related …
[HTML][HTML] Endpoints for clinical trials in ophthalmology
L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …
ophthalmology has increased. Visual acuity has for a long time been considered the gold …
Retinal oximetry: metabolic imaging for diseases of the retina and brain
E Stefánsson, OB Olafsdottir, TS Eliasdottir… - Progress in retinal and …, 2019 - Elsevier
Retinal oximetry imaging of retinal blood vessels measures oxygen saturation of
hemoglobin. The imaging technology is non-invasive and reproducible with remarkably low …
hemoglobin. The imaging technology is non-invasive and reproducible with remarkably low …
Anatomical and functional changes in the retina in patients with Alzheimer's disease and mild cognitive impairment
S Szegedi, P Dal‐Bianco, E Stögmann… - Acta …, 2020 - Wiley Online Library
Purpose There is evidence that mild cognitive impairment (MCI) or Alzheimer's disease (AD)
is accompanied by alterations in the retina. The current study was performed to investigate …
is accompanied by alterations in the retina. The current study was performed to investigate …
[HTML][HTML] Ocular blood flow measurements in healthy white subjects using laser speckle flowgraphy
N Luft, PA Wozniak, GC Aschinger, K Fondi, AM Bata… - PloS one, 2016 - journals.plos.org
Purpose To assess the feasibility and reliability of Laser Speckle Flowgraphy (LSFG) to
measure ocular perfusion in a sample of healthy white subjects and to elucidate the age …
measure ocular perfusion in a sample of healthy white subjects and to elucidate the age …
Assessment of flow dynamics in retinal and choroidal microcirculation
Alterations in ocular blood flow have been implicated in mechanisms that lead to vision loss
in patients with various ocular disorders such as diabetic retinopathy, glaucoma, and age …
in patients with various ocular disorders such as diabetic retinopathy, glaucoma, and age …
[HTML][HTML] Retinal oxygen extraction in individuals with type 1 diabetes with no or mild diabetic retinopathy
K Fondi, PA Wozniak, K Howorka, AM Bata… - Diabetologia, 2017 - Springer
Aims/hypothesis The aim of this study was to compare retinal oxygen extraction in
individuals with diabetes with no or mild non-proliferative diabetic retinopathy and healthy …
individuals with diabetes with no or mild non-proliferative diabetic retinopathy and healthy …
Total retinal blood flow measurement by three beam Doppler optical coherence tomography
We present measurements of total retinal blood flow in healthy volunteers using a three
beam Doppler optical coherence tomography (D-OCT) technique. This technology has the …
beam Doppler optical coherence tomography (D-OCT) technique. This technology has the …