Engineering the multiscale complexity of vascular networks

C O'Connor, E Brady, Y Zheng, E Moore… - Nature Reviews …, 2022 - nature.com
The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …

Whole-organ tissue engineering: decellularization and recellularization of three-dimensional matrix scaffolds

SF Badylak, D Taylor, K Uygun - Annual review of biomedical …, 2011 - annualreviews.org
The definitive treatment for end-stage organ failure is orthotopic transplantation. However,
the demand for transplantation far exceeds the number of available donor organs. A …

Complex heterogeneous tissue constructs containing multiple cell types prepared by inkjet printing technology

T Xu, W Zhao, JM Zhu, MZ Albanna, JJ Yoo, A Atala - Biomaterials, 2013 - Elsevier
This study was designed to develop a versatile method for fabricating complex and
heterogeneous three-dimensional (3D) tissue constructs using simultaneous ink-jetting of …

In vitro models for liver toxicity testing

VY Soldatow, EL LeCluyse, LG Griffith… - Toxicology …, 2013 - academic.oup.com
Over the years, various liver-derived in vitro model systems have been developed to enable
investigation of the potential adverse effects of chemicals and drugs. Liver tissue slices …

Hydrogels in biology and medicine: from molecular principles to bionanotechnology

NA Peppas, JZ Hilt, A Khademhosseini… - Advanced …, 2006 - Wiley Online Library
Hydrophilic polymers are the center of research emphasis in nanotechnology because of
their perceived “intelligence”. They can be used as thin films, scaffolds, or nanoparticles in a …

Micropatterning as a tool to decipher cell morphogenesis and functions

M Théry - Journal of cell science, 2010 - journals.biologists.com
In situ, cells are highly sensitive to geometrical and mechanical constraints from their
microenvironment. These parameters are, however, uncontrolled under classic culture …

Soft lithography in biology and biochemistry

GM Whitesides, E Ostuni, S Takayama… - Annual review of …, 2001 - annualreviews.org
▪ Abstract Soft lithography, a set of techniques for microfabrication, is based on printing and
molding using elastomeric stamps with the patterns of interest in bas-relief. As a technique …

[HTML][HTML] Scaffolds for tissue fabrication

PX Ma - Materials today, 2004 - Elsevier
Tissue engineering is an interdisciplinary and multidisciplinary field. It has shown great
promise in generating living alternatives for harvested tissues and organs for transplantation …

Microscale technologies for tissue engineering and biology

A Khademhosseini, R Langer… - Proceedings of the …, 2006 - National Acad Sciences
Microscale technologies are emerging as powerful tools for tissue engineering and
biological studies. In this review, we present an overview of these technologies in various …

Co-culture systems and technologies: taking synthetic biology to the next level

L Goers, P Freemont, KM Polizzi - Journal of The Royal …, 2014 - royalsocietypublishing.org
Co-culture techniques find myriad applications in biology for studying natural or synthetic
interactions between cell populations. Such techniques are of great importance in synthetic …