Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that affects multiple
organ systems and is caused by loss-of-function mutations in one of two genes: TSC1 or …

Lymphangioleiomyomatosis (LAM) is a rare progressive lung disease of women. LAM is
caused by mutations in the tuberous sclerosis genes, resulting in activation of the mTOR …

Background Lymphangioleiomyomatosis (LAM) is a progressive, cystic lung disease in
women; it is associated with inappropriate activation of mammalian target of rapamycin …

Background: Lymphangioleiomyomatosis (LAM) is a rare cystic lung disease that primarily
affects women. The purpose of these guidelines is to provide recommendations for the …

Perivascular epithelioid cell neoplasms: pathology and pathogenesis - ScienceDirect Skip
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The last century experienced remarkable advances in the classification, diagnosis, and
understanding of the pathogenesis of the interstitial lung diseases. Technological advances …

Lymphangioleiomyomatosis (LAM) is a rare, cystic lung disease that is associated with
mutations in tuberous sclerosis genes, renal angiomyolipomas, lymphatic spread, and …

Rationale: Lymphangioleiomyomatosis (LAM) is a metastatic neoplasm of reproductive-age
women associated with mutations in tuberous sclerosis complex genes. LAM causes cystic …

Lymphangioleiomyomatosis (LAM) is a progressive cystic lung disease primarily affecting
women that has historically been classified and clinically managed as a nonneoplastic …

Lymphangioleiomyomatosis (LAM) is an often fatal disease primarily affecting young women
in which tuberin (TSC2)-null cells metastasize to the lungs. The mechanisms underlying the …