Navigating the liver landscape: upcoming pharmacotherapies for primary sclerosing cholangitis

HN Pham, L Pham, K Sato - Expert Opinion on Pharmacotherapy, 2024 - Taylor & Francis
Introduction Primary sclerosing cholangitis (PSC) is a bile duct disorder characterized by
ductular reaction, hepatic inflammation, and liver fibrosis. The pathogenesis of PSC is still …

Controversy over the atherogenicity of lipoprotein-X

T Miida, S Hirayama - Current Opinion in Endocrinology, Diabetes …, 2019 - journals.lww.com
Lp-X is heterogeneous in apoE content. Lp-X is taken up in cholestatic patients by apoE-
recognizing lipoprotein receptors. Further research is warranted to fully understand the …

Clinical laboratory characteristics of patients with obstructive jaundice accompanied by dyslipidemia

Y Zhao, S Wang, S Liang, H Zhang, Y Zhang, R Yu… - Clinical …, 2021 - Elsevier
Background Abnormal lipid metabolism manifests as hypercholesterolemia in patients with
obstructive jaundice due to lipoprotein X (LpX). Our aim was to explore the clinical …

[HTML][HTML] Diffuse xanthomas in a patient with primary biliary cholangitis and lipoprotein X

J Harris, S Cao, G Hile, M Eshaq - JAAD Case Reports, 2021 - Elsevier
Cutaneous xanthomas are common cutaneous lesions that arise from localized deposits of
lipid in the dermis. 1 Their presence often represents an underlying disorder of lipid …

[HTML][HTML] Detection of Lipoprotein X (LpX): A challenge in patients with severe hypercholesterolaemia

A Ćwiklińska, A Mickiewicz, R Kowalski… - Journal of medical …, 2020 - ncbi.nlm.nih.gov
Background Lipoprotein X (LpX) is an abnormal lipoprotein fraction, which can be detected
in patients with severe hypercholesterolaemia and cholestatic liver disease. LpX is …

A High-Throughput NMR Method for Lipoprotein-X Quantification

E Garcia, I Shalaurova, SP Matyus, LA Freeman… - Molecules, 2024 - mdpi.com
Lipoprotein X (LP-X) is an abnormal cholesterol-rich lipoprotein particle that accumulates in
patients with cholestatic liver disease and familial lecithin–cholesterol acyltransferase …

Case report: Unusual and extremely severe lipoprotein X-mediated hypercholesterolemia in extrahepatic pediatric cholestasis

R Colantuono, C Pavanello, A Pietrobattista… - Frontiers in …, 2022 - frontiersin.org
Background Lipoprotein X (LpX)-mediated extremely severe hyperlipidemia is a possible
feature detectable in children with syndromic paucity of intralobular bile ducts (Alagille …

Lipoprotein-X disease in the setting of severe cholestatic hepatobiliary autoimmune disease

RE Heinl, HM Tennant, JC Ricketts, CR Rice… - Journal of Clinical …, 2017 - Elsevier
Lipoprotein-X disease in the setting of severe cholestatic hepatobiliary autoimmune disease
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Use of therapeutic plasma exchange to remove lipoprotein X in a patient with vanishing bile duct syndrome presenting with cholestasis, pseudohyponatremia, and …

Y Jung, HA Nelson, DMH Lin - Journal of Clinical Apheresis, 2024 - Wiley Online Library
Abstract Introduction Lipoprotein X (Lp‐X) is an abnormal lipoprotein found in multiple
disease conditions, including liver dysfunction and cholestasis. High Lp‐X concentrations …

Lipoprotein X in autoimmune liver disease causing interference in routine and specialist biochemical investigations

N Rao, A Jain, A Goyale, JW Persaud… - Clinical …, 2017 - Taylor & Francis
Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are chronic,
immune-mediated diseases which may be associated with the presence of lipoprotein X …