Calcinosis cutis is the deposition of insoluble calcium in the skin and subcutaneous tissues.
It represents a major clinical problem in patients with SSc affecting at least one quarter of …

Cytokines and growth factors are key regulators of immune activation, vascular alteration
and excessive production of extracellular matrix which are hallmark events in the …

Objective To determine the relationships between systemic sclerosis (SSc)–related
autoantibodies, as well as their clinical associations, in a well‐characterized Australian …

Objective. IVIG is known to confer significant benefit in rheumatologic conditions, including
inflammatory myopathy. This study aimed to assess the efficacy of IVIG across different …

Scleroderma: the role of serum autoantibodies in defining sp... : Current Opinion in
Rheumatology Scleroderma: the role of serum autoantibodies in defining specific clinical …

Objective Calcinosis is a debilitating complication of systemic sclerosis (SSc) with no
effective treatments. We sought to identify clinical correlations and to characterize …

Objective. To assess the clinical manifestations and prognosis of Spanish patients with
systemic sclerosis (SSc) according to their immunological profile. Methods. From the …

Introduction/Objectives A line blot (LB) assay is a multi-analyte platform capable of
simultaneously detecting multiple anti-nuclear antibody specificities. Here, we evaluated the …

Calcinosis is a frequent complication of systemic sclerosis (SSc) that is usually located in
extremities but may occur across the board. The aim of our study was to identify and quantify …

Objective Autoantibody profiles in systemic sclerosis (SS c) and their relative clinical
association vary between studies. The rate for being anti‐topoisomerase‐I (ATA) positive …