Vagus nerve as modulator of the brain–gut axis in psychiatric and inflammatory disorders

S Breit, A Kupferberg, G Rogler, G Hasler - Frontiers in psychiatry, 2018 - frontiersin.org
The vagus nerve represents the main component of the parasympathetic nervous system,
which oversees a vast array of crucial bodily functions, including control of mood, immune …

Metabolic flexibility as an adaptation to energy resources and requirements in health and disease

RL Smith, MR Soeters, RCI Wüst… - Endocrine …, 2018 - academic.oup.com
The ability to efficiently adapt metabolism by substrate sensing, trafficking, storage, and
utilization, dependent on availability and requirement, is known as metabolic flexibility. In …

The human islet: mini-organ with mega-impact

JT Walker, DC Saunders, M Brissova… - Endocrine …, 2021 - academic.oup.com
This review focuses on the human pancreatic islet—including its structure, cell composition,
development, function, and dysfunction. After providing a historical timeline of key …

Therapeutic potential of targeting the ghrelin pathway

G Colldén, MH Tschöp, TD Müller - International Journal of Molecular …, 2017 - mdpi.com
Ghrelin was discovered in 1999 as the endogenous ligand of the growth-hormone
secretagogue receptor 1a (GHSR1a). Since then, ghrelin has been found to exert a plethora …

Altilix® Supplement Containing Chlorogenic Acid and Luteolin Improved Hepatic and Cardiometabolic Parameters in Subjects with Metabolic Syndrome: A 6 Month …

G Castellino, D Nikolic, A Magán-Fernández, GA Malfa… - Nutrients, 2019 - mdpi.com
The objective was to evaluate the effects of 6 months of supplementation with Altilix®,
containing chlorogenic acid and its derivatives, and luteolin and its derivatives, on …

New insights on the relationship between leptin, ghrelin, and leptin/ghrelin ratio enforced by body mass index in obesity and diabetes

AV Sitar-Tǎut, A Cozma, A Fodor, SC Coste… - Biomedicines, 2021 - mdpi.com
Currently, adipose tissue is considered an endocrine organ, however, there are still many
questions regarding the roles of adipokines—leptin and ghrelin being two adipokines. The …

[HTML][HTML] Physiology, obesity neurohormonal appetite and satiety control

AY Yeung, P Tadi - 2020 - europepmc.org
The feelings of appetite and satiety involve complex interactions between hormones from
the gastrointestinal (GI) tract to the hypothalamus and subsequent feedback. Within the …

Acylated and desacyl ghrelin are associated with hepatic lipogenesis, β-oxidation and autophagy: role in NAFLD amelioration after sleeve gastrectomy in obese rats

S Ezquerro, L Méndez-Giménez, S Becerril… - Scientific reports, 2016 - nature.com
Bariatric surgery improves non-alcoholic fatty liver disease (NAFLD). Our aim was to
investigate the potential role of ghrelin isoforms in the resolution of hepatic steatosis after …

The effects of plant-derived oleanolic acid on selected parameters of glucose homeostasis in a diet-induced pre-diabetic rat model

M Gamede, L Mabuza, P Ngubane, A Khathi - Molecules, 2018 - mdpi.com
Prolonged exposure to high energy diets has been implicated in the development of pre-
diabetes, a long-lasting condition that precedes type 2 diabetes mellitus (T2DM). A …

[HTML][HTML] Neuromechanism of acupuncture regulating gastrointestinal motility

Z Yu - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
Acupuncture has been used in China for thousands of years and has become more widely
accepted by doctors and patients around the world. A large number of clinical studies and …